ReviewFrontiers in cellular neuroscience2026
The research landscape of ferroptosis in ischemic stroke: a bibliometric analysis of the literature from 2017 to 2025 based on the WOS and PubMed databases.
Review in Frontiers in cellular neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Ischemic stroke is a leading cause of disability and mortality worldwide. Ferroptosis-an iron-dependent, lipid peroxidation-driven programmed cell death-has emerged as a key contributor to post-stroke neuronal injury, with research expanding rapidly since 2017. Objective: This study employs bibliometric methods to systematically analyze literature on ferroptosis in ischemic stroke from 2017 to 2025, aiming to elucidate the field's development trajectory, research hotspots, emerging frontiers, and collaborative networks. Methods: Data were retrieved from the Web of Science Core Collection and PubMed, limited to English articles and reviews published between 2017 and 2025. For PubMed, an additional search was conducted to capture empirical studies on ferroptosis inhibitors. Bibliometric analyses were performed using VOSviewer, CiteSpace, and Bibliometrix R package. Results: A total of 646 WoS-indexed articles were analyzed. Annual publication output showed exponential growth. China, the United States, and India led in publication volume, with China accounting for over half of global output; international collaboration centered on China-US partnerships. Research hotspots focused on molecular mechanisms (GPX4, System Xc Conclusion: From 2017 to 2025, research on ferroptosis in ischemic stroke has rapidly evolved from concept introduction and mechanistic exploration toward clinical translation. Bibliometric analysis delineates a clear trajectory and evolving knowledge framework. Future research will likely emphasize interdisciplinary integration, clinical translation, and personalized therapeutic strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.