Evidence map›Paper›PMID 42719521›Full record

ReviewSAGE open medicine2026

Prevalence, multidrug resistance patterns, and carbapenemase-encoding genes of carbapenemase-producing

Chalachew Genet, Wendemagegn Enbiale, Anna Rommerskirchen, Addisu Melese, Baye Yirga Adugna, Zeleke Ayenew, Hiwot Tadesse, Bayeh Abera, Endalkachew Nibret, Abaineh Munshea Abitew

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in SAGE open medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chalachew GenetHealth Biotechnology Division, Institute of Biotechnology, Bahir Dar University, Bahir Dar, Ethiopia.ORCID https://orcid.org/0000-0001-8631-5094
Wendemagegn EnbialeEpiGen Ethiopia, Bahir Dar University, Bahir Dar, Ethiopia.
Anna RommerskirchenInstitute of Medical Microbiology and Hospital Hygiene, Heinrich-Heine-University, Düsseldorf, Germany.
Addisu MeleseDepartment of Medical Microbiology, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.
Baye Yirga AdugnaHealth Biotechnology Division, Institute of Biotechnology, Bahir Dar University, Bahir Dar, Ethiopia.
Zeleke AyenewTB, Mycology and Other Bacterial Research Division, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.
Hiwot TadesseDepartment of Medical Microbiology, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.
Bayeh AberaDepartment of Medical Microbiology, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.
Endalkachew NibretHealth Biotechnology Division, Institute of Biotechnology, Bahir Dar University, Bahir Dar, Ethiopia.ORCID https://orcid.org/0000-0002-7063-2877
Abaineh Munshea AbitewHealth Biotechnology Division, Institute of Biotechnology, Bahir Dar University, Bahir Dar, Ethiopia.ORCID https://orcid.org/0000-0002-1469-2189

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Carbapenems are considered the last resort to treat life-threatening bacterial infections. However, their efficacy is increasingly compromised by carbapenemase-producing Methods: A systematic search was conducted in electronic databases for studies published in English up to June 30, 2025. The review followed PRISMA guidelines and included 44 eligible studies. Quality assessment was performed using the Joanna Briggs Institute (JBI) checklist. The meta-analysis was performed using Comprehensive Meta-Analysis (CMA) software version 2, applying a random-effects model to estimate pooled prevalence. Heterogeneity and publication bias were evaluated using the I Results: The pooled prevalence of CPKP and/or CPEC in Ethiopia was 8.3% (95% CI: 6.3-10.9; I Conclusions: This study reveals a high pooled prevalence of CPKP and CPEC in Ethiopia and high dominance of the

Indexed as

carbapenem-resistanceEnterobacteriaceaeEscherichia coliEthiopiaK. pneumoniaemetallo-β-lactamaseone health

Identifiers

PMID42719521
PMCPMC13554686

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.