Evidence map›Paper›PMID 42719429›Full record

ArticleSAGE open medicine2026

Predictive values of IGF1, IGFBP3 and PCT for patients with sepsis-induced acute respiratory distress syndrome.

Yanhuo Xia, Yihua Dong, Songzan Qian, Qiuling Tong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in SAGE open medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yanhuo XiaDepartment of Intensive Care Unit, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Yihua DongDepartment of Intensive Care Unit, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Songzan QianDepartment of Intensive Care Unit, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Qiuling TongDepartment of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.ORCID https://orcid.org/0009-0003-5231-9953

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To explore the predictive value of serum IGF1, IGFBP3 and PCT for the development and prognosis of sepsis-induced ARDS. Methods: A total of 276 septic patients enrolled were divided into an ARDS group (144 cases) and a non-ARDS control group (132 cases). On admission, APACHE II and SOFA Scores were calculated, and serum PCT, IGF1, and IGFBP3 were measured. The differences of clinical and biomarkers between groups were analyzed using a Mann-Whitney Results: Compared with controls, patients with sepsis-induced ARDS exhibited significantly lower serum IGFBP3 and IGF1 but higher PCT concentrations. Serum IGFBP3 was negatively correlated with APACHE II scores ( Conclusion: Aberrant expressions of circulating IGF1, IGFBP3 and PCT are closely linked to the severity in patients with sepsis-induced ARDS. The combination of serum PCT and IGF1, and SOFA scores had a good predictive performance for identifying septic patients at high risk of ARDS. Serum IGFBP3 can serve as a valuable biomarker to evaluate the outcomes of sepsis-induced ARDS.

Indexed as

acute respiratory distress syndromeinsulin-like growth factor-1insulin-like growth factor binding proteins-3procalcitoninsepsis

Identifiers

PMID42719429
PMCPMC13554602

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.