Evidence map›Paper›PMID 42719408›Full record

ReviewJournal of ginseng research2026

Ginseng polysaccharides: Structures-based classification and biological activities-A review.

Hancong Shao, Yanjun Yang, Dandan Zhu, Zhonghuan Qu, Bin Huang, Xiaobin Jia, Bing Yang, Liang Feng

Abstract readReview
In one paragraph

Review in Journal of ginseng research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hancong ShaoSchool of Traditional Chinese Pharmacy, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 211198, PR China.
Yanjun YangSchool of Traditional Chinese Pharmacy, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 211198, PR China.
Dandan ZhuSchool of Traditional Chinese Pharmacy, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 211198, PR China.
Zhonghuan QuSchool of Traditional Chinese Pharmacy, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 211198, PR China.
Bin HuangSchool of Traditional Chinese Pharmacy, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 211198, PR China.
Xiaobin JiaSchool of Traditional Chinese Pharmacy, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 211198, PR China.
Bing YangSchool of Traditional Chinese Pharmacy, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 211198, PR China.
Liang FengSchool of Traditional Chinese Pharmacy, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 211198, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ginseng polysaccharides are primarily categorized into two group: acidic polysaccharides, which are composed of rhamnogalacturonan I and homogalacturonan domains, and neutral polysaccharides, primarily consisting of glucans. These polysaccharides exhibit valuable pharmacological activities, including immunomodulation, antitumor effects, and antioxidant properties. Numerous studies have confirmed that structural characteristics such as weight-average molecular weight, monosaccharide composition, and structural domains of ginseng polysaccharides are closely related to their biological activities. However, research on the correlation between these factors remains fragmented, lacking a systematic integration that elucidates their intrinsic connections. This paper provides a comprehensive review of the structural features and biological activities of ginseng polysaccharides, with a particular focus on their structure-activity relationships. Furthermore, it summarizes the patterns of physical, biological, and chemical transformations of ginseng polysaccharide structures and the resulting changes in their biological activity. We hope this paper provides a theoretical basis and insights for the clinical application and product development of ginseng polysaccharides.

Indexed as

Biological activityGinseng polysaccharidesStructural transformationStructureStructure-activity relationships

Identifiers

PMID42719408
PMCPMC13554455

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.