Evidence map›Paper›PMID 42719404›Full record

ArticleExperimental and therapeutic medicine2026

PDK1/AKT signaling is involved in the anti-tumor effect of gramine and cisplatin chemoresistance in ovarian cancer cells.

Haiyan Wang, Ruiming Zheng, Bujun Wang, Sumiao Hong, Hongxia Chen

Abstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Haiyan WangDepartment of Obstetrics and Gynecology, Pingyang People's Hospital, Wenzhou, Zhejiang 325400, P.R. China.
Ruiming ZhengDepartment of Obstetrics and Gynecology, Pingyang People's Hospital, Wenzhou, Zhejiang 325400, P.R. China.
Bujun WangDepartment of Obstetrics and Gynecology, Pingyang People's Hospital, Wenzhou, Zhejiang 325400, P.R. China.
Sumiao HongDepartment of Obstetrics and Gynecology, Pingyang People's Hospital, Wenzhou, Zhejiang 325400, P.R. China.
Hongxia ChenDepartment of Obstetrics and Gynecology, Pingyang People's Hospital, Wenzhou, Zhejiang 325400, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ovarian cancer (OC) remains one of the most lethal gynecologic malignancies, with limited therapeutic options and poor long-term prognosis. Gramine, an indole alkaloid predominantly derived from the rhizomes of

Indexed as

AKTcisplatingramineovarian cancerPDK1

Identifiers

PMID42719404
PMCPMC13554652

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.