Evidence map›Paper›PMID 42719241›Full record

ReviewFrontiers in cellular and infection microbiology2026

The current studies on the mechanisms of lactic acid bacteria as probiotics in the alleviate of bovine diseases: a review.

Chun-Ling Guo, Lin-Yue Zhou, Shun-Yi Ji, Han-Jia Zhang, Zhi-Rui Ren, Xiao Tang, Hao Dong, Qing-Feng Meng

Abstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chun-Ling GuoCollege of Life Sciences, Jilin Agricultural University, Changchun, Jilin, China.
Lin-Yue ZhouCollege of Life Sciences, Jilin Agricultural University, Changchun, Jilin, China.
Shun-Yi JiCollege of Life Sciences, Jilin Agricultural University, Changchun, Jilin, China.
Han-Jia ZhangCollege of Life Sciences, Jilin Agricultural University, Changchun, Jilin, China.
Zhi-Rui RenCollege of Life Sciences, Jilin Agricultural University, Changchun, Jilin, China.
Xiao TangCollege of Life Sciences, Jilin Agricultural University, Changchun, Jilin, China.
Hao DongCollege of Life Sciences, Jilin Agricultural University, Changchun, Jilin, China.
Qing-Feng MengCollege of Life Sciences, Jilin Agricultural University, Changchun, Jilin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lactic acid bacteria (LAB) are an encouraging probiotic option to antibiotics in treating typical bovine diseases, including but not limited to, mastitis, inflammatory bowel disease, diarrhea, and endometritis. The review discusses the therapeutic mechanisms of LAB in a systematic manner including competitive exclusion of pathogens, synthesis of antimicrobial products such as organic acids, bacteriocins, and short-chain fatty acids, recovery of mucosal barrier integrity by regulating tight junctions, and suppression of pro-inflammatory pathways, such as NF-κB and MAPK, to modulate the host immune response. All these mechanisms lower the inflammation, improve the condition of the gut and mammary glands and increase the level of productivity. LAB are an effective and long-term solution to decrease the consumption of antibiotics and antibiotic resistance. This review will form a theoretical basis of introducing LAB into veterinary practice and promote sustainable animal husbandry.

Indexed as

Cattle DiseasesLactobacillalesProbioticsAnimalsCattleFemaleIntestinal Barrier Functionbovine diseasesgut microbiotaimmunoregulationlactic acid bacteria (LAB)mucosal barrierprobiotics

Identifiers

PMID42719241
PMCPMC13556053

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.