ArticleFrontiers in cardiovascular medicine2026
The relationship between skeletal muscle mass and cardiac structure in elderly male inpatients.
Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: To investigate the associations of skeletal muscle mass index (SMI) and handgrip strength with cardiac structure and function in elderly male inpatients without severe acute cardiovascular conditions. Methods: This cross-sectional study included 143 male inpatients aged ≥60 years. SMI was assessed using dual-energy x-ray absorptiometry, handgrip strength was measured by electronic dynamometry, and cardiac structure and function were evaluated by two-dimensional echocardiography. Multivariable linear regression and restricted cubic spline models were performed to assess the associations between skeletal muscle characteristics and echocardiographic parameters. Results: Compared with the normal-SMI group, participants with low SMI had significantly smaller ARD, LVEDD, and LVESD (all Discussion: In elderly male inpatients, SMI was independently and linearly associated with left ventricular structure and systolic function, whereas handgrip strength showed fewer significant associations with cardiac parameters. These observational findings suggest that SMI may represent a potential marker of age-related left ventricular structural changes; however, longitudinal studies are required to determine the temporal relationship and clinical implications.
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