Evidence map›Paper›PMID 42719139›Full record

ArticleFrontiers in bioengineering and biotechnology2026

Graphene quantum dots remodel osteogenesis of human periodontal ligament stem cells under inflammatory microenvironment: an

Sicheng Deng, Xiaona Wu, Shaoyong Chen, Yulu Xie, Lingsan Ran, Haiyan Xue, Qiuling Pang, Kuangdi Xin, Yuehua You, Rongmin Qiu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sicheng Deng *College and Hospital of Stomatology, Guangxi Medical University, Guangxi Key Laboratory of Oral and Maxillofacial Rehabilitation and Reconstruction, Guangxi Clinical Research Center for Craniofacial Deformity, Guangxi Key Laboratory of Oral and Maxillofacial Surgery Disease Treatment, Guangxi Health Commission Key Laboratory of Prevention and Treatment for Oral Infectious Diseases, Key Laboratory of Research and Application of Stomatological Equipment, Education Department of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, China.
Xiaona Wu *College and Hospital of Stomatology, Guangxi Medical University, Guangxi Key Laboratory of Oral and Maxillofacial Rehabilitation and Reconstruction, Guangxi Clinical Research Center for Craniofacial Deformity, Guangxi Key Laboratory of Oral and Maxillofacial Surgery Disease Treatment, Guangxi Health Commission Key Laboratory of Prevention and Treatment for Oral Infectious Diseases, Key Laboratory of Research and Application of Stomatological Equipment, Education Department of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, China.
Shaoyong Chen *College and Hospital of Stomatology, Guangxi Medical University, Guangxi Key Laboratory of Oral and Maxillofacial Rehabilitation and Reconstruction, Guangxi Clinical Research Center for Craniofacial Deformity, Guangxi Key Laboratory of Oral and Maxillofacial Surgery Disease Treatment, Guangxi Health Commission Key Laboratory of Prevention and Treatment for Oral Infectious Diseases, Key Laboratory of Research and Application of Stomatological Equipment, Education Department of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, China.
Yulu XieCollege and Hospital of Stomatology, Guangxi Medical University, Guangxi Key Laboratory of Oral and Maxillofacial Rehabilitation and Reconstruction, Guangxi Clinical Research Center for Craniofacial Deformity, Guangxi Key Laboratory of Oral and Maxillofacial Surgery Disease Treatment, Guangxi Health Commission Key Laboratory of Prevention and Treatment for Oral Infectious Diseases, Key Laboratory of Research and Application of Stomatological Equipment, Education Department of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, China.
Lingsan RanCollege and Hospital of Stomatology, Guangxi Medical University, Guangxi Key Laboratory of Oral and Maxillofacial Rehabilitation and Reconstruction, Guangxi Clinical Research Center for Craniofacial Deformity, Guangxi Key Laboratory of Oral and Maxillofacial Surgery Disease Treatment, Guangxi Health Commission Key Laboratory of Prevention and Treatment for Oral Infectious Diseases, Key Laboratory of Research and Application of Stomatological Equipment, Education Department of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, China.
Haiyan XueCollege and Hospital of Stomatology, Guangxi Medical University, Guangxi Key Laboratory of Oral and Maxillofacial Rehabilitation and Reconstruction, Guangxi Clinical Research Center for Craniofacial Deformity, Guangxi Key Laboratory of Oral and Maxillofacial Surgery Disease Treatment, Guangxi Health Commission Key Laboratory of Prevention and Treatment for Oral Infectious Diseases, Key Laboratory of Research and Application of Stomatological Equipment, Education Department of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, China.
Qiuling PangCollege and Hospital of Stomatology, Guangxi Medical University, Guangxi Key Laboratory of Oral and Maxillofacial Rehabilitation and Reconstruction, Guangxi Clinical Research Center for Craniofacial Deformity, Guangxi Key Laboratory of Oral and Maxillofacial Surgery Disease Treatment, Guangxi Health Commission Key Laboratory of Prevention and Treatment for Oral Infectious Diseases, Key Laboratory of Research and Application of Stomatological Equipment, Education Department of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, China.
Kuangdi XinCollege and Hospital of Stomatology, Guangxi Medical University, Guangxi Key Laboratory of Oral and Maxillofacial Rehabilitation and Reconstruction, Guangxi Clinical Research Center for Craniofacial Deformity, Guangxi Key Laboratory of Oral and Maxillofacial Surgery Disease Treatment, Guangxi Health Commission Key Laboratory of Prevention and Treatment for Oral Infectious Diseases, Key Laboratory of Research and Application of Stomatological Equipment, Education Department of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, China.
Yuehua YouKey Laboratory of Longhua, Department of Stomatology, Longhua People's Hospital, Shenzhen, China.
Rongmin QiuCollege and Hospital of Stomatology, Guangxi Medical University, Guangxi Key Laboratory of Oral and Maxillofacial Rehabilitation and Reconstruction, Guangxi Clinical Research Center for Craniofacial Deformity, Guangxi Key Laboratory of Oral and Maxillofacial Surgery Disease Treatment, Guangxi Health Commission Key Laboratory of Prevention and Treatment for Oral Infectious Diseases, Key Laboratory of Research and Application of Stomatological Equipment, Education Department of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aims to provide experimental basis that underpins the potential application of graphene quantum dots (GQDs) as a therapeutic strategy for periodontitis. Methods and Materials: An inflammatory circumstance was established by Porphyromonas gingivalis lipopolysaccharide (P.g-LPS). The effects of GQDs on human periodontal ligament stem cells (hPDLSCs) proliferation, migration and osteogenic differentiation Result: Conclusion: GQDs possess the capacity to counteract inflammation-induced damage and promote osteogenic restoration both

Indexed as

alveolar bone regenerationgraphene quantum dotshuman periodontal ligament stem cellmigrationosteogenic differentiationperiodontitisproliferation

Identifiers

PMID42719139
PMCPMC13553934

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.