SynthesisFrontiers in microbiology2026
Antibacterial and antibiofilm activities of pyocins produced by
Synthesis in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Antimicrobial resistance among Gram-negative bacteria, particularly Objectives: To systematically evaluate evidence on the extraction, purification, characterization, antibacterial activity, antibiofilm efficacy, and resistance mechanisms of pyocins against Gram-negative bacteria. Methods: This review followed PRISMA 2020 guidelines and was registered in PROSPERO (ID: CRD420251064333). PubMed, Scopus, Web of Science, and CINAHL databases were searched for studies published between January 2015 and June 2025. Eligible studies included Results: A total of 191 records were identified; 137 were screened after duplicate removal, and 7 studies met the inclusion criteria. Pyocins demonstrated strong antibacterial activity against Conclusion: Pyocins exhibit potent antibacterial and antibiofilm activity and represent promising alternatives to conventional antibiotics. However, standardized methodologies,
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.