Evidence map›Paper›PMID 42719107›Full record

ArticleAnnals of thoracic surgery short reports2026

Real-time Myocardial Oximetry-Preclinical Monitoring Device Validation in a Porcine Beating-Heart Cardiopulmonary Bypass Model.

Eetu Haavisto, Henri Haapanen, Liisa Petäjä, Peter Raivio, Esko Kankuri, Mikko Jormalainen, Kalle Kotilahti, Tatu Juvonen, Tommi Pätilä

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In one paragraph

Article in Annals of thoracic surgery short reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Eetu HaavistoFaculty of Medicine, Department of Pharmacology, University of Helsinki, Helsinki, Finland.
Henri HaapanenPediatric Cardiac Surgery, Children's Hospital, Helsinki University Hospital, and University of Helsinki, Helsinki, Finland.
Liisa PetäjäDepartment of Anesthesiology, Heart and Lung Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Peter RaivioDepartment of Cardiac Surgery, Heart and Lung Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Esko KankuriFaculty of Medicine, Department of Pharmacology, University of Helsinki, Helsinki, Finland.
Mikko JormalainenDepartment of Cardiac Surgery, Heart and Lung Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Kalle KotilahtiDepartment of Neuroscience and Biomedical Engineering, Aalto University, School of Science, Espoo, Finland.
Tatu JuvonenDepartment of Cardiac Surgery, Heart and Lung Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Tommi PätiläPediatric Cardiac Surgery, Children's Hospital, Helsinki University Hospital, and University of Helsinki, Helsinki, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Continuous, real-time monitoring of myocardial oxygenation during cardiac surgery holds potential for enhancing patient safety and improving outcomes. This study evaluated the precision of the near-infrared spectroscopy-based SpectroCor Ltd monitoring device, which measures myocardial hemoglobin/myoglobin (Hb/Mb) oxygen saturation and cytochrome c oxidase (CcO) oxidation ratio. Description: Yorkshire pigs, under general anesthesia, were subjected to cardiopulmonary bypass to generate graded myocardial desaturation. Graded desaturation at aortic root was induced by mixing oxygenated blood from partly pumping cardiopulmonary bypass with deoxygenated blood passing nonventilated lungs. SpectroCor myocardial oximetry was validated against blood samples drawn simultaneously from the aortic root and coronary sinus during various stable saturation intervals. Evaluation: With accuracy of 5.3 percentage points, the SpectroCor device's myocardial Hb/Mb oxygen saturation readings tightly correlated with reference blood samples. Concurrent changes in CcO oxidation ratio closely mirrored Hb/Mb saturation, indicating reliable assessment of mitochondrial function. Conclusions: The SpectroCor monitoring device provides accurate, real-time measurements of myocardial oxygenation, supporting its potential to help optimize cardioprotective strategies during cardiac surgery.

Identifiers

PMID42719107
PMCPMC13555410

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.