ArticleFrontiers in cardiovascular medicine2026
Myocardial function recovery in peripartum cardiomyopathy: the role of global longitudinal strain and myocardial work.
Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05878041 (Creation of a Multicenter National Registry for Peripartum Cardiomyopathy), which is not on this map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Creation of a Multicenter National Registry for Peripartum Cardiomyopathy: a Wide, Multidisciplinary and Translational Perspective to Achieve Personalized Medicine for a Rare Disease in Women
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
28 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Peripartum cardiomyopathy (PPCM) occurs during the peripartum period or shortly thereafter and is characterised by left ventricular (LV) systolic dysfunction. Although some women achieve recovery of LV ejection fraction (LVEF), others develop persistent systolic impairment. Data on myocardial mechanics and contractile performance after the acute phase are limited. Aim: We aimed to evaluate whether global longitudinal strain (GLS) and myocardial work (MW) indices could provide a more comprehensive assessment of myocardial performance and identify subtle abnormalities associated with incomplete myocardial recovery in PPCM. Methods: We retrospectively analysed 22 women (mean age 42.1 ± 8.9 years) with PPCM, evaluated ≥6 months after the acute phase, enrolled in the Italian Multicentre Observational PPCM Registry (NCT05878041). Myocardial mechanics were assessed using GLS, global work index, global constructive work, global wasted work, and global work efficiency (GWE). Patients were stratified by LVEF into Group A (<50%) and Group B (≥50%) and compared with 21 age-matched healthy women (Group C). Results: LV recovery was observed in 16 women (72.7%). Compared with controls, Groups A and B displayed larger LV diameters and volumes ( Conclusions: GLS and MW indices enable a refined assessment of myocardial performance in PPCM. Persistent abnormalities despite normalised LVEF suggest residual subclinical dysfunction and support their potential role as sensitive markers of myocardial impairment beyond conventional measures of systolic function.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.