Evidence map›Paper›PMID 42718924›Full record

ArticleFrontiers in immunology2026

Severe thrombocytopenia is associated with arterial thrombotic manifestations in antiphospholipid syndrome: a two-center cohort study.

Jie Kong, Yijing Su, Xinyun Zhu, Jingjing Zhao, Haojie Chen, Xiaoxiang Chen, Yingying Gao

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jie Kong *Department of Rheumatology and Immunology, Nantong First People's Hospital, Southeast University, Nantong, Jiangsu, China.
Yijing Su *Department of Rheumatology and Immunology, Affiliated Nantong Clinical College of Nantong University, Nantong First People's Hospital, Nantong, Jiangsu, China.
Xinyun Zhu *Department of Rheumatology and Immunology, Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jingjing ZhaoDepartment of Rheumatology and Immunology, Nantong First People's Hospital, Southeast University, Nantong, Jiangsu, China.
Haojie ChenDepartment of Rheumatology and Immunology, Nantong First People's Hospital, Southeast University, Nantong, Jiangsu, China.
Xiaoxiang ChenDepartment of Allergy and Immunology, Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yingying GaoDepartment of Rheumatology and Immunology, Nantong First People's Hospital, Southeast University, Nantong, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Thrombocytopenia in APS is often regarded primarily as a bleeding-related manifestation, but the relationship between platelet-count severity and thrombotic manifestations remains uncertain. We evaluated the association between severe thrombocytopenia and arterial thrombotic manifestations in patients with antiphospholipid syndrome (APS). Methods: In a two-center baseline cohort of 313 patients with APS, baseline platelet count (PLT) was categorized as PLT <50×10 Results: PLT <50×10 Conclusion: Severe thrombocytopenia was associated with arterial thrombotic manifestations in APS, particularly cerebral infarction. PLT <50×10

Indexed as

Antiphospholipid SyndromeThrombocytopeniaThrombosisAdultCohort StudiesFemaleHumansMaleMiddle AgedPlatelet CountPrevalenceRisk FactorsSeverity of Illness Indexantiphospholipid antibodiesantiphospholipid syndromearterial thrombosiscerebral infarctionthrombocytopenia

Identifiers

PMID42718924
PMCPMC13553740

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.