Evidence map›Paper›PMID 42718836›Full record

ArticleFrontiers in bioengineering and biotechnology2026

Electrophoretic deposition of hydroxyapatite-capsaicin nanocomposite coatings on Mg-Ag alloy: effects on microstructure, hardness, and proliferation/chondrogenic differentiation of adipose-derived stem cells.

Xinyi Shi, Taihua Wang, Jianjun Qiao

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xinyi ShiTianjin University, Guangdong Cell Biotechnology Co., LTD., Dongguan, Guangdong, China.
Taihua WangGuangdong Cell Biotechnology Co., LTD., Shenzhen Taihua Cell Biotechnology Co., LTD., Dongguan, Guangdong, China.
Jianjun QiaoCollege of Chemical Engineering, Tianjin University, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper explores the fabrication of hydroxyapatite-capsaicin nanocomposite coatings on Mg-Ag alloy by the electrophoretic deposition (EPD) method at different deposition times and voltages. The microstructure, surface chemistry, hardness, corrosion behavior, and cell proliferation of the deposited layers at different deposition times and voltages were examined. Based on microstructural observations, the deposited layers became denser at higher deposition time and voltage. In addition, the hydroxyapatite-capsaicin nanocomposite became thicker at higher EPD voltage. FTIR and XPS analyses confirmed the successful incorporation of capsaicin into the HAP coating with partial retention of CAP-derived surface functionalities after annealing. Also, the hardness of the coated layer increased with voltage and time. However, EPD voltage was more effective in increasing the hardness. The maximum hardness of 141 HV was obtained at a deposition voltage of 160 V. The hardness profile of the deposited composite showed greater fluctuations with increasing deposition voltage. Electrochemical polarization tests demonstrated that corrosion resistance improved with increasing deposition voltage and time. Furthermore, cell growth was improved at higher EPD time and voltage. MTT assay results confirmed the enhanced cytocompatibility of the HAP-CAP coatings. Also, the Mg

Indexed as

adipose-derived stem cellchondrogenic differentiationcompositedepositionhydroxyapatite

Identifiers

PMID42718836
PMCPMC13553550

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.