Trial reportFrontiers in dental medicine2026
Innovative herbal oil formulation as a pre-prosthetic mucosal conditioner: a prospective controlled cytological study on the degree of keratinization in edentulous ridge mucosa before and after Its topical application.
Trial report in Frontiers in dental medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
7 authors.
Funding
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Abstract
Background: Adequate keratinization of the edentulous ridge is fundamental for denture support, retention, stability, and mucosal resilience. This study evaluated the effect of topical Moringa oleifera stem bark oil on oral mucosal keratinization in edentulous ridges using a prospective controlled clinical trial design with a water-massage control group. Methods: One hundred and eight completely edentulous participants were enrolled between April 2025 and September 2025: a treatment group ( Results: The treatment group demonstrated a significant progressive increase in superficial keratinized cells, from a median of 57.5 at T0 to 114.0 at T4 [Friedman Conclusion: Topical Moringa oleifera stem bark oil was associated with a significant increase in cytological markers of keratinization, with no change in the water-massage control group, and descriptively demonstrated favourable Clinical Trial Registration: (https://ctri.nic.in) CTRI/2025/04/084650; Patent Publication No. 202241052361.
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