EpCAM aptamer modified carbon@manganese dioxide nanoflower for synergistic drug-nanozyme allergic rhinitis treatment.

Leichao Zhang, Longying Cong, Yiyao Gao, Wei Zhang, Yiting Liu, Lingyu Zhang, Qian Xiu

Abstract read

In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Leichao ZhangDepartment of Pathology, China-Japan Union Hospital of Jilin University, 126 Xian Tai Street, Changchun, Jilin, 130000, PR China.

Longying CongDepartment of Chemistry, Northeast Normal University, 5268 Ren Min Street, Changchun, Jilin, 130024, PR China.

Yiyao GaoDepartment of Scientific Research Center, China-Japan Union Hospital, Jilin University, 126 Xian Tai Street, Changchun, Jilin, 130000, PR China.

Wei ZhangDepartment of Chemistry, Northeast Normal University, 5268 Ren Min Street, Changchun, Jilin, 130024, PR China.

Yiting LiuDepartment of Otolaryngology-Head and Neck Surgery, China-Japan Union Hospital, Jilin University, 126 Xian Tai Street, Changchun, Jilin, 130000, PR China.

Lingyu ZhangDepartment of Chemistry, Northeast Normal University, 5268 Ren Min Street, Changchun, Jilin, 130024, PR China.

Qian XiuDepartment of Otolaryngology-Head and Neck Surgery, China-Japan Union Hospital, Jilin University, 126 Xian Tai Street, Changchun, Jilin, 130000, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allergic rhinitis (AR) is a prevalent upper respiratory allergic disorder that significantly impacts patients' quality of life.In this research, we developed a multifunctional nanozyme-drug synergistic therapy nanosystem for the treatment of allergic rhinitis (AR). The nanosystem, called EpCAM aptamer modified carbon@manganese dioxide nanoflower (Apt-C@MnO

Indexed as

Allergic rhinitisBudesonideEpCAM aptamerNanozymeReactive oxygen species (ROS)Targeted drug delivery

Identifiers

PMID42718604

DOI10.1016/j.mtbio.2026.103588

PMCPMC13553565

What OpenQuestion holds

Textmetadata

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.