ArticleFrontiers in surgery2026
Comparative tissue response to a bovine peritoneum matrix and UltraPro mesh under experimental
Article in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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9 authors.
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Abstract
Background/objectives: Biologic extracellular matrix (ECM) implants are investigated for abdominal wall reconstruction because they may support tissue remodeling while limiting persistent foreign-body reactions. However, their response to contamination with multidrug-resistant pathogens remains insufficiently characterized. This exploratory study compared a bovine-derived peritoneum ECM scaffold with UltraPro mesh in a rat model of Methods: Thirty outbred rats were included. Twenty-four animals underwent ECM or UltraPro implantation and were evaluated on postoperative days 10 and 20 ( Results: All animals survived, and no clinically evident wound infection, dehiscence, or abscess formation was observed. On day 10, ECM demonstrated greater necrosis and polymorphonuclear-cell infiltration than UltraPro. By day 20, ECM showed reduced necrosis, increased cellular colonization, and greater reticulin fiber deposition, consistent with early tissue organization. UltraPro demonstrated increasing multinucleated giant-cell activity, fibrosis, granulomatous inflammation, and capsule formation. Conventional culture did not recover viable Conclusions: Under experimental
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