Evidence map›Paper›PMID 42718458›Full record

ArticleFrontiers in neurology2026

Prevalence and factors associated with post-stroke depression: a cross-sectional analysis of a prospectively assembled cohort in Eastern Saudi Arabia.

Aishah Albakr, Mustafa Alqarni, Ali Alhashim, Dalal Albakr, Zakia Yasawy, Omar Al Ghamdi, Erum Sharif, Rizwana Shahid, Azra Zafar, Saima Nazish and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Aishah AlbakrDepartment of Neurology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Mustafa AlqarniDepartment of Neurology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Ali AlhashimDepartment of Neurology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Dalal AlbakrDepartment of Psychiatry, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Zakia YasawyDepartment of Neurology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Omar Al GhamdiDepartment of Neurology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Erum SharifDepartment of Neurology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Rizwana ShahidDepartment of Neurology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Azra ZafarDepartment of Neurology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Saima NazishDepartment of Neurology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Wa'ad Massoud Almunassir AlqahtaniDepartment of Neurology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Dana AljameaDepartment of Neurology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Fahad AldamighDepartment of Neurology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Fahad AlDawsariDepartment of Neurology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.
Ziyad Al GhannamDepartment of Neurology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To estimate the prevalence and severity of post-stroke depression (PSD) and identify factors independently associated with PSD among stroke survivors. Methods: This cross-sectional analysis was conducted within a prospectively assembled hospital-based cohort at King Fahd University Hospital between January 2021 and November 2025. Adults with ischemic stroke, transient ischemic attack, intracerebral hemorrhage, or cerebral venous sinus thrombosis (CVST) underwent PSD assessment at least 3 months after the index event. PSD was established through structured clinical assessment based on DSM-5-TR and ICD-11 criteria together with the clinician-administered 17-item Hamilton Depression Rating Scale. Factors associated with PSD were evaluated using forced-entry multivariable logistic regression. Results: Among 403 participants, the mean age was 57.3 ± 13.8 years, and 69.2% were male. PSD was identified in 172 participants (42.7%): 71 (17.6%) had mild, 61 (15.1%) moderate, and 40 (9.9%) severe or very severe depression. The complete-case multivariable analysis included 398 participants. Higher NIHSS score was independently associated with PSD [adjusted odds ratio (aOR) per 1-point increase, 1.35; 95% CI, 1.22-1.49; Conclusion: PSD affected approximately two-fifths of participants and was most consistently associated with neurological severity and functional disability. Standardized depression screening should be integrated into post-stroke care, particularly for patients with greater neurological impairment or functional dependence. The CVST finding was exploratory and requires confirmation.

Indexed as

DepressionStrokeAdultAgedCohort StudiesCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalenceProspective StudiesRisk FactorsSaudi Arabiadepression screeningfunctional disabilityneurological severityNIHSS (National Institute of Health Stroke Scale)post-stroke depressionSaudi Arabia

Identifiers

PMID42718458
PMCPMC13553280

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.