Evidence map›Paper›PMID 42717503›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Structural Divergence Between the Moltbook AI-Agent Network and Human Social Networks.

Wenpin Hou, Zhicheng Ji

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Wenpin HouDepartment of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, North Carolina, USA.ORCID https://orcid.org/0000-0003-0972-2192
Zhicheng JiDepartment of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, North Carolina, USA.ORCID https://orcid.org/0000-0002-9457-4704

Funding

Methods for inferring and analyzing gene regulatory networks using single-cell multiomics and spatial genomics dataR35GM150887 · NIGMS · DUKE UNIVERSITY · PI Wenpin Hou · 2023 to 2026
$1.6M
Computational methods for in situ spatial transcriptomicsR35GM154865 · NIGMS · DUKE UNIVERSITY · PI Zhicheng Ji · 2024 to 2026
$1.2M
Computational Methods for Inferring Single-cell DNA Methylation and its Spatial LandscapeR00HG011468 · NHGRI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HOU, WENPIN · 2022 to 2024
$747k
NHGRI NIH HHS R00 HG011468NIGMS NIH HHS R35 GM150887NIGMS NIH HHS R35 GM154865NIH HHS R00HG011468NIH HHS R35GM150887NIH HHS R35GM154865
6 · The paper itself

Abstract

Large populations of artificial intelligence (AI) agents are increasingly embedded in online environments, yet little is known about how their collective interaction patterns compare to human social systems. Here, we analyze the full interaction network of Moltbook, an agent-native platform in which AI agents interact through posts and comments, and systematically compare its structure to well-characterized human communication networks. Although Moltbook follows the same node-edge scaling relationship observed in human systems, indicating comparable global growth constraints, its internal organization diverges markedly. The network exhibits extreme attention inequality, heavy-tailed, and asymmetric degree distributions, suppressed reciprocity, and a global under-representation of connected triadic structures. Community analysis reveals a structured modular architecture with elevated modularity and comparatively lower community size inequality relative to degree-preserving null models. Together, these findings show that the Moltbook agent-platform system reproduces global structural regularities of human networks while exhibiting a distinct internal organization, highlighting that key features of social network structure can vary substantially across interaction environments.

Indexed as

agent‐based modelartificial intelligencecommunications systemcommunity structurecomputer scienceinteraction networklanguage modelmodularitysocial network analysissocial relation

Identifiers

PMID42717503
PMCPMC13558904

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.