Evidence map›Paper›PMID 42717206›Full record

ArticleNature communications2026

Zinc displacement and metabolic interference: cobalt ion-mediated therapy for broad-spectrum CRKP-resistant pneumonia via inhalable microspheres.

Zhaoyou Chu, Jun Liang, Yayun Wu, Wanyue Fu, Ling Xu, Hanqing Zhang, Jiyang Wang, Min Shao, Haisheng Qian

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhaoyou Chu *School of Biomedical Engineering, Anhui Medical University, Hefei, China.ORCID http://orcid.org/0000-0002-6741-385X
Jun Liang *School of Biomedical Engineering, Anhui Medical University, Hefei, China.ORCID http://orcid.org/0009-0008-1094-3180
Yayun Wu *Department of Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Anhui Medical University, Hefei, China.
Wanyue FuSchool of Pharmaceutical Sciences, Anhui Medical University, Hefei, China.ORCID http://orcid.org/0009-0004-2713-628X
Ling XuSchool of Biomedical Engineering, Anhui Medical University, Hefei, China.
Hanqing ZhangSchool of Biomedical Engineering, Anhui Medical University, Hefei, China.
Jiyang WangDepartment of Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Anhui Medical University, Hefei, China.ORCID http://orcid.org/0009-0007-5992-6958
Min ShaoDepartment of Critical Care Medicine, The First Affiliated Hospital of Anhui Medical University, Anhui Medical University, Hefei, China. shaomin@ahmu.edu.cn.ORCID http://orcid.org/0000-0001-7307-5570
Haisheng QianSchool of Biomedical Engineering, Anhui Medical University, Hefei, China. shqian@ahmu.edu.cn.ORCID http://orcid.org/0000-0003-4903-3447

Funding

Anhui Department of Education (Department of Education of Anhui Province) 2025AHGXZK40264China Postdoctoral Science Foundation 2023M740029National Natural Science Foundation of China (National Science Foundation of China) 82572403
6 · The paper itself

Abstract

Currently, broad-spectrum carbapenem-resistant Klebsiella pneumoniae (CRKP) infectious pneumonia remains clinically difficult to treat. This study develops inhalable microspheres (SCM) loaded with meropenem (MEM), fabricated via microfluidics by cross-linking sodium alginate with Co

Indexed as

Anti-Bacterial AgentsCobaltKlebsiella InfectionsKlebsiella pneumoniaePneumonia, BacterialZincAdministration, InhalationAnimalsHumansLungMeropenemMiceMicrobial Sensitivity TestsMicrospheresAnti-Bacterial AgentsCobaltMeropenemZinc

Identifiers

PMID42717206
PMCPMC13558701

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.