ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2026
A head-to-head comparison of health utilities and measurement properties of the EQ-5D-5L and SF-6Dv2 among people living with HIV in China.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
purposeTo compare health utilities and measurement properties of the EQ-5D-5L and SF-6Dv2 among people living with HIV (PLHIV) in China, and to identify factors associated with utility values.
methodsA multicenter cross-sectional survey was conducted among PLHIV in Shandong, Guangdong, and Sichuan provinces. Utilities were calculated using Chinese value sets. Ceiling/floor effects were evaluated. Convergent validity and agreement were assessed using Spearman's rank correlation, intraclass correlation coefficients (ICC), and Bland-Altman (B-A) plots. Known-groups validity and discriminative performance were evaluated using effect sizes and relative efficiency. Tobit models identified factors associated with utilities.
resultsAmong 705 respondents, mean (SD) utilities were 0.93 (0.15) for EQ-5D-5L and 0.80 (0.17) for SF-6Dv2. Ceiling effects were higher for EQ-5D-5L than SF-6Dv2 (48.2 vs. 14.3%). The instruments showed good convergent validity (r = 0.719) and agreement (ICC = 0.729), but the B-A limits of agreement spanned 0.48, exceeding the instrument-defined minimally important difference (MID) of 0.06. Both instruments discriminated across known groups. The EQ-5D-5L had higher relative efficiency for comorbid chronic disease, CD4 + T-cell counts, and prior HIV self-testing experience, whereas the SF-6Dv2 had higher relative efficiency for duration of ART, economic burden, and self-rated health. Comorbid chronic disease, no prior HIV self-testing experience, and heavy economic burden were associated with lower utility values.
conclusionsBoth instruments showed acceptable measurement properties among Chinese PLHIV, but systematic utility differences suggest they should not be used interchangeably. These findings support objective-driven instrument selection and may inform cost-utility analyses and utility-improvement targets.
Indexed as
Identifiers
42717154What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.