Evidence map›Paper›PMID 42717127›Full record

SynthesisPlant foods for human nutrition (Dordrecht, Netherlands)2026

Functional and Nutritional Potential of Chickpea Protein Hydrolysates: A Systematic Review and Plant-protein Network Analysis.

Noelia M Rodríguez-Martín, José Carlos Márquez-López, María-Soledad Fernández-Pachón, Justo Pedroche

Abstract readSystematic Review
In one paragraph

Synthesis in Plant foods for human nutrition (Dordrecht, Netherlands), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Noelia M Rodríguez-MartínDepartment of Biological and Health Sciences, Faculty of Health Sciences, Loyola University (Universidad Loyola Andalucía), Avda. de las Universidades s/n, Dos Hermanas, 41704, Spain. nmrodriguez@uloyola.es.ORCID http://orcid.org/0000-0003-4737-2330
José Carlos Márquez-LópezPlant Protein Group, Instituto de la Grasa-CSIC, Avda. Rectora Rosario Valpuesta nº 1, Dos Hermanas Seville, 41089, Spain.ORCID http://orcid.org/0009-0004-1497-2625
María-Soledad Fernández-PachónÁrea de Nutrición y Bromatología, Departamento de Biología Molecular e Ingeniería Bioquímica, Universidad Pablo de Olavide, Avda. Rectora Rosario Valpuesta nº 1, Dos Hermanas Seville, 41089, Spain.ORCID http://orcid.org/0000-0002-9524-298X
Justo PedrochePlant Protein Group, Instituto de la Grasa-CSIC, Avda. Rectora Rosario Valpuesta nº 1, Dos Hermanas Seville, 41089, Spain. j.pedroche@csic.es.ORCID http://orcid.org/0000-0002-2562-3779

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chickpea is a protein-rich legume increasingly explored as a substrate for functional plant-based ingredients. Chickpea protein hydrolysates (CPHs) and chickpea-derived peptides (CPs), obtained through enzymatic hydrolysis or simulated gastrointestinal digestion, may provide technological and biological properties while supporting the valorization of chickpea fractions and by-products. This review integrates a network analysis of title-abstract terms from 5,728 unique Scopus and PubMed records on plant protein hydrolysates with a systematic review of 72 studies focused on CPH production, peptide characterization, bioactivity, and translational gaps. The evidence indicates that CPHs and CPs show promising antioxidant, antihypertensive, antidiabetic, anti-inflammatory, lipid-lowering, immunomodulatory, antimicrobial, and anticancer-related activities, mainly supported by biochemical assays, cell models, and animal studies. However, heterogeneous hydrolysis protocols, incomplete peptide characterization, inconsistent bioactivity methods, limited scale-up evidence, and the absence of human intervention trials restrict translation. Future studies should prioritize standardized protocols, mechanistic validation, bioavailability, sensory and regulatory assessment, food-matrix validation, and clinical trials.

Indexed as

CicerNutritive ValuePlant ProteinsProtein HydrolysatesAnimalsAntioxidantsBioactive Peptides, DietaryFunctional FoodHumansHydrolysisAntioxidantsBioactive Peptides, DietaryPlant ProteinsProtein HydrolysatesBibliometric mappingBioactive propertiesCicer arietinumEnzymatic hydrolysisPlant-based ingredientsPreclinical evidenceSimulated gastrointestinal digestion

Identifiers

PMID42717127
PMCPMC13558302

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.