Evidence map›Paper›PMID 42717091›Full record

ArticleNature2026

PLA2G2D in tumour-draining lymph nodes regulates anti-tumour immunity.

Anneloes van Krimpen, Julie Huang, Mike Eterman, Vivian Gerretsen, Michihisa Umetani, Josephine C Janssen, Menno van Nimwegen, Nina Rozendaal, Thierry P P van den Bosch, Xinguo Jiang and 25 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Anneloes van Krimpen *Department of Pulmonary Medicine, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.ORCID http://orcid.org/0000-0002-3226-0961
Julie Huang *Apeximmune Therapeutics, Burlingame, CA, USA.ORCID http://orcid.org/0009-0003-8025-8713
Mike EtermanDepartment of Pulmonary Medicine, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.ORCID http://orcid.org/0009-0004-8676-7292
Vivian GerretsenDepartment of Pulmonary Medicine, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.ORCID http://orcid.org/0000-0003-0307-8287
Michihisa UmetaniApeximmune Therapeutics, Burlingame, CA, USA.ORCID http://orcid.org/0000-0001-8474-7088
Josephine C JanssenErasmus MC Cancer Institute, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.
Menno van NimwegenDepartment of Pulmonary Medicine, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.
Nina RozendaalDepartment of Pulmonary Medicine, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.ORCID http://orcid.org/0009-0008-2653-7849
Thierry P P van den BoschDepartment of Pathology, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.
Xinguo JiangApeximmune Therapeutics, Burlingame, CA, USA.ORCID http://orcid.org/0000-0003-3266-9238
Kathryn LogronioApeximmune Therapeutics, Burlingame, CA, USA.
Angela Z LiuApeximmune Therapeutics, Burlingame, CA, USA.
Yun-Ru LiuTaipei Medical University, Taipei City, Taiwan.
Yuki NagasakiCenter for Disease Biology and Integrative Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
Makoto MurakamiCenter for Disease Biology and Integrative Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.ORCID http://orcid.org/0000-0002-4565-6017
Anne Onrust-Van SchoonhovenDepartment of Pulmonary Medicine, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.
Asabi LeliveldDepartment of Pulmonary Medicine, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.ORCID http://orcid.org/0009-0005-7967-1222
Disha VadgamaDepartment of Pulmonary Medicine, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.
Hedwig LangeveldDepartment of Pulmonary Medicine, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.
Rogier van WijckDepartment of Pathology, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.
Eric BindelsDepartment of Haematology, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.ORCID http://orcid.org/0000-0001-9502-669X
Jan von der ThüsenDepartment of Pathology, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.ORCID http://orcid.org/0000-0001-9699-4860
Antien MooyaartDepartment of Pathology, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.
Febe van MaldegemDepartment of Molecular Cell Biology and Immunology, Amsterdam UMC, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0002-2544-544X
Claudia M BrenisLaboratory of Immunoregulation and Mucosal Immunology, VIB-UGent Centre for Inflammation Research, Ghent, Belgium.ORCID http://orcid.org/0000-0001-8462-8652
Stijn VerwaerdeLaboratory of Immunoregulation and Mucosal Immunology, VIB-UGent Centre for Inflammation Research, Ghent, Belgium.ORCID http://orcid.org/0000-0002-1398-8746
Rudi W HendriksDepartment of Pulmonary Medicine, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.ORCID http://orcid.org/0000-0003-2291-0382
Bart N LambrechtDepartment of Pulmonary Medicine, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.
Dirk J GrünhagenErasmus MC Cancer Institute, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.ORCID http://orcid.org/0000-0001-8293-6002
Cornelis VerhoefErasmus MC Cancer Institute, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.ORCID http://orcid.org/0000-0001-9980-8613
Joachim G J V AertsDepartment of Pulmonary Medicine, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.ORCID http://orcid.org/0000-0001-6662-2951
Li-Fen LeeApeximmune Therapeutics, Burlingame, CA, USA. llee@apeximmune.com.ORCID http://orcid.org/0009-0003-0390-7388
Kan V LuApeximmune Therapeutics, Burlingame, CA, USA. klu@apeximmune.com.ORCID http://orcid.org/0009-0005-1279-7621
Ralph StadhoudersDepartment of Pulmonary Medicine, Erasmus MC University Medical Centre, Rotterdam, The Netherlands. r.stadhouders@erasmusmc.nl.ORCID http://orcid.org/0000-0002-1060-5607
Floris DammeijerDepartment of Pulmonary Medicine, Erasmus MC University Medical Centre, Rotterdam, The Netherlands. f.dammeijer@erasmusmc.nl.ORCID http://orcid.org/0000-0002-8648-5306

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic anti-tumour immunity results from T cell priming in tumour-draining lymph nodes (TDLNs)

Identifiers

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.