Evidence map›Paper›PMID 42717081›Full record

ArticleNature2026

A serpin-myeloid axis in pancreatic cancer heterogeneity and immune evasion.

Chiara Falcomatà, Maximilian M Schaefer, Bhavya Singh, Divya Chhamalwan, Alexander Tepper, Sebastian R Nielsen, Hunter T Potak, Maxime Dhainaut, Gurkan Mollaoglu, Matthew D Park and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Chiara FalcomatàIcahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Maximilian M Schaefer *Icahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0002-6038-7847
Bhavya Singh *Icahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0001-6641-6429
Divya ChhamalwanIcahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Alexander TepperIcahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Sebastian R NielsenIcahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Hunter T PotakIcahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Maxime DhainautIcahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Gurkan MollaogluIcahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Matthew D ParkPrecision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0003-3488-3262
Miriam MeradPrecision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0002-4481-7827
Alessia BaccariniIcahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Brian D BrownIcahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. brian.brown@mssm.edu.ORCID http://orcid.org/0000-0002-3670-8778

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic ductal carcinoma (PDAC) is characterized by a highly immunosuppressive, extracellular matrix-rich microenvironment, yet tumours display marked heterogeneity

Identifiers

PMID42717081

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.