Evidence map›Paper›PMID 42716675›Full record

SynthesisThe clinical respiratory journal2026

Advancements in Immunotherapy for Lung Cancer: A Meta-Analysis of Clinical Trial Outcomes.

Yingjie Jiao, Yan Zhao

Abstract readMeta-Analysis
In one paragraph

Synthesis in The clinical respiratory journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yingjie JiaoBoshan Shantou Health Center, Zibo, China.
Yan ZhaoDepartment of Cadiothoracic Surgery, Zibo First Hospital, Zibo, China.ORCID https://orcid.org/0009-0000-1693-5917

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune checkpoint inhibitors (ICIs) have changed therapeutic selections for advanced non-small cell lung cancer (NSCLC). However, comparative evidence versus chemotherapy through ICI monotherapy and chemo-immunotherapy combination strategies remains incomplete. For this purpose, we conducted a meta-analysis of randomized controlled trials (RCTs) to measure overall survival (OS) and progression-free survival (PFS) outcome improvements in ICI monotherapy or ICI-chemotherapy combined treatment. These interventions take place in adults (≥ 18 years) with advanced/metastatic NSCLC. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses directions were obeyed. PubMed, Scopus, and Web of Science were searched (2021-2024) for RCTs. A total of 7849 articles were retrieved. RCTs (n = 17) qualify inclusion. Hazard ratios (HRs) along with 95% confidence intervals (CIs) for OS and PFS were pooled using random-effects models. The heterogeneity was assessed by I

Indexed as

Carcinoma, Non-Small-Cell LungImmune Checkpoint InhibitorsImmunotherapyLung NeoplasmsAntineoplastic Combined Chemotherapy ProtocolsHumansProgression-Free SurvivalRandomized Controlled Trials as TopicTreatment OutcomeImmune Checkpoint Inhibitorschemo‐immunotherapyimmune checkpoint inhibitorsnon–small cell lung canceroverall survivalprogression‐free survival

Identifiers

PMID42716675
PMCPMC13557920

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.