Evidence map›Paper›PMID 42716578›Full record

ArticleBMJ open respiratory research2026

Short-term exposure to heat associated with lower lung function in older adults: analysis of the Lung VITAL cohort.

Nicholas Nassikas, Wenli Ni, Heike Luttmann-Gibson, Vadim Bubes, Antonella Zanobetti, Brent Coull, Julie E Buring, JoAnn E Manson, Diane R Gold, Mary B Rice

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open respiratory research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nicholas NassikasDivision of Pulmonary, Critical Care, and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA nnassika@bidmc.harvard.edu.ORCID http://orcid.org/0000-0002-0798-3703
Wenli NiCenter for Climate, Health, and the Global Environment, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.ORCID http://orcid.org/0000-0003-2355-8464
Heike Luttmann-GibsonDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Vadim BubesDivision of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Antonella ZanobettiDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Brent CoullDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Julie E BuringDivision of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
JoAnn E MansonDivision of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Diane R GoldDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Mary B RiceDivision of Pulmonary, Critical Care, and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.

Funding

Harvard Clinical and Translational Science CenterUL1TR001102 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2013 to 2017
$106.2M
Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI Marc G Weisskopf · 1985 to 2026
$44.6M
VITamin D and omegA-3 triaL (VITAL)U01CA138962 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI BURING, JULIE E., MANSON, JOANN ELISABETH · 2009 to 2014
$23.6M
The VITamin D and OmegA-3 TriaL (VITAL)R01CA138962 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI BURING, JULIE E., MANSON, JOANN ELISABETH · 2015 to 2019
$20.9M
The VITamin D and OmegA-3 TriaL (VITAL): Post-Intervention Follow-UpR01AT011729 · NCCIH · BRIGHAM AND WOMEN'S HOSPITAL · PI Jun Li, JoAnn Elisabeth Manson · 2021 to 2026
$5.2M
Effects of vitamin D and omega-3 fatty acids on infectious diseases and hCAP18R01AI093723 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI CAMARGO, CARLOS ARTURO · 2011 to 2015
$4.0M
Lung VITamin D and OmegA-3 TriaL (Lung VITAL)R01HL101932 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI GOLD, DIANE R · 2010 to 2014
$3.2M
Climate Variability and Respiratory Health in Asthma and COPDK23ES035863 · NIEHS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI Nicholas Nassikas · 2024 to 2026
$769k
NCATS NIH HHS UL1 TR001102NCCIH NIH HHS R01 AT011729NCI NIH HHS R01 CA138962NCI NIH HHS U01 CA138962NHLBI NIH HHS R01 HL101932NIAID NIH HHS R01 AI093723NIEHS NIH HHS K23 ES035863NIEHS NIH HHS P30 ES000002
6 · The paper itself

Abstract

backgroundHigh temperatures are associated with respiratory symptoms, hospitalisations and mortality. Yet, the effects on lung function are not well described. The aim of this study was to determine associations of acute exposure to high temperatures with lung function in adults.

methodsWe included 1923 study participants from Lung VITamin D and OmegA-3 TriaL (VITAL) cohort, an ancillary study of VITAL, who underwent spirometry (two per participant) between 2010 and 2018. We assigned daily mean temperature, relative humidity, air pollution to geocoded participant home addresses. Forced expiratory volume in 1 s (FEV

resultsMedian (IQR) daily mean temperature was 13.6°C (17.4°C) for the study population. Daily exposures moderately correlated (r

conclusionsShort-term exposure to high temperatures over the preceding 7 days was associated with lower lung function in older US adults. Increases in heat exposure warrant interventions to protect older adults.

Indexed as

Environmental ExposureHot TemperatureLungAgedCohort StudiesFemaleForced Expiratory VolumeHumansHumidityMaleMiddle AgedSpirometryUnited StatesVital CapacityAsthma EpidemiologyClinical EpidemiologyRespiratory Measurement

Identifiers

PMID42716578
PMCPMC13560994

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.