Evidence map›Paper›PMID 42715520›Full record

ReviewChemMedChem2026

Exploring the Anticancer Potential of Schiff Base Complexes: A Mini-Review.

Atif Ahmad, Anam, Marcos V Palmeira-Mello, Sabir Khan, José Clayston Melo Pereira

Abstract readReview
In one paragraph

Review in ChemMedChem, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Atif AhmadDepartamento de Química Analítica, Físico-Química e Inorgânica, Instituto de Química, UNESP - Universidade Estadual Paulista, Araraquara, Brazil.ORCID https://orcid.org/0009-0003-6669-5503
AnamDepartamento de Química Analítica, Físico-Química e Inorgânica, Instituto de Química, UNESP - Universidade Estadual Paulista, Araraquara, Brazil.ORCID https://orcid.org/0009-0006-3792-1163
Marcos V Palmeira-MelloDepartamento de Química, Universidade Federal de São Carlos (UFSCar), São Carlos, Brazil.ORCID https://orcid.org/0000-0003-2550-5315
Sabir KhanUniversidade Federal de Pelotas (UFPel), Pelotas, Brazil.ORCID https://orcid.org/0000-0003-4557-238X
José Clayston Melo PereiraDepartamento de Química Analítica, Físico-Química e Inorgânica, Instituto de Química, UNESP - Universidade Estadual Paulista, Araraquara, Brazil.ORCID https://orcid.org/0000-0002-1647-5575

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schiff bases are well known for their ability to form stable coordination compounds with several transition metals, making them valuable for medicinal chemistry purposes. These metal-based compounds have attracted significant attention due to their enhanced biological activities, particularly their ability to act toward anticancer chemotherapy. This mini-review provides a comprehensive overview of Schiff base complexes reported over the last 5 years, highlighting the recent advances related to their biological investigations. Cytotoxicity and interactions with biological targets have been detailed. The mechanisms underlying the capacity of these complexes to induce cell death in cancer cells are also described.

Indexed as

Antineoplastic AgentsCoordination ComplexesNeoplasmsCell ProliferationHumansMolecular StructureSchiff BasesAntineoplastic AgentsCoordination ComplexesSchiff Basescytotoxicity on tumor cell linesDNA binding modesinducing cell death mechanismsSchiff base metal complexes

Identifiers

PMID42715520
PMCPMC13557718

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.