In one paragraphArticle in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
14 authors.
DeNard V SimmonsDepartment of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.ORCID 0000-0002-9829-4312 Oscar Andrés Moreno-RamosAligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.ORCID 0000-0002-1378-2545 Divya D A RajAligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.ORCID 0000-0003-0268-1500 Konstantin KaganovskyDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0002-1577-109X Arin PamukcuDepartment of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Nora VrielerDepartment of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.ORCID 0000-0002-8008-7884 Tatiana TkatchDepartment of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.ORCID 0000-0001-6626-7435 Zhong XieDepartment of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.ORCID 0000-0002-8348-4455 Ana Isabel Silva de SousaDepartment of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.ORCID 0000-0003-3749-043X Enrico ZampeseDepartment of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.ORCID 0000-0002-8851-2566 Jun DingAligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.ORCID 0000-0003-0690-1312 Rajeshwar AwatramaniAligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA.ORCID 0000-0002-0713-2140 Charles J WilsonDepartment of Neuroscience, Developmental and Regenerative Biology, University of Texas at San Antonio, San Antonio, TX 78249, USA.ORCID 0000-0002-9004-2145 D James SurmeierDepartment of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Funding
Determinants of Basal Ganglia Pathology in Parkinson's DiseaseR01NS121174 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BEVAN, MARK D, SURMEIER, DALTON JAMES · 2021 to 2025
$3.6MNINDS NIH HHS R01 NS121174
6 · The paper itselfAbstract
Recent studies have implicated dopaminergic signaling within the substantia nigra pars reticulata (SNr) in the emergence of Parkinsonian motor deficits. To better understand the mechanisms underlying this dependence, the ability of dopamine to modulate SNr neuron activity was studied in ex vivo mouse brain slices. In addition to presynaptically inhibiting phasic GABA release, D2 dopamine receptor (D2R) signaling unexpectedly suppressed a tonic, GABA
Indexed as
AstrocytesDopamineDopaminergic Neuronsgamma-Aminobutyric AcidSignal TransductionSubstantia NigraAldehyde Dehydrogenase 1 FamilyAnimalsGABA Plasma Membrane Transport ProteinsMiceReceptors, Dopamine D2Receptors, GABA-ARetinal DehydrogenaseSynaptic TransmissionAldehyde Dehydrogenase 1 FamilyALDH1A1 protein, mouseDopamineGABA Plasma Membrane Transport Proteinsgamma-Aminobutyric AcidReceptors, Dopamine D2Receptors, GABA-ARetinal Dehydrogenase
Identifiers
PMID42715320
PMCPMC13557058
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