ArticlePloS one2026
Clinicopathological characteristics and prognosis of melanoma: A retrospective cohort study in Xinjiang, China.
Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
The incidence of melanoma is substantially lower in Asians than in Caucasians. This study retrospectively analyzed 355 patients in Xinjiang, China, to delineate the clinicopathological features and prognosis of melanoma in this region. The median overall survival (OS) and disease-free survival (DFS) were 78.0 and 46.0 months with 1-, 3-, and 5-year OS/DFS rates of 83.3%/68.3%/57.0% and 80.4%/59.5%/43.4%, respectively. Multivariate analysis identified advanced AJCC stage and elevated LDH as independent predictors of poorer OS. For DFS, AJCC stage, presence of metastasis, elevated LDH, and aCCI predicted worse outcomes, while adjuvant therapy was protective. Crucially, subtype-specific determinants emerged: aCCI independently predicted OS (HR = 18.42, P = 0.005) and DFS (HR = 4.91, P = 0.019) in CM, while higher BMI was associated with poorer DFS in AM (HR = 3.58, P = 0.019). These findings underscore the need for subtype-aware clinical management in this region.
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