Evidence map›Paper›PMID 42715170›Full record

Observational studyPloS one2026

Fathers at risk: Effects of threatened and actual preterm birth on the course of paternal peripartum depression and anxiety.

Valia Pernidaki, Karin Schermelleh-Engel, Sarah Sommerlad, Frank Louwen, Silvia Oddo-Sommerfeld

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01974531 (Psychological Distress & Stress in Parents With Preterm infants-a Prospective Study on Risk and Protective Psychobiological Aspects), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01974531 completednot on this map

Psychological Distress & Stress in Parents With Preterm infants-a Prospective Study on Risk and Protective Psychobiological Aspects

Typeobservational_patient_registrySponsorJohann Wolfgang Goethe University HospitalRan2013 to 2019Enrolled400ConditionsPreterm Birth, Pregnancy, Stress, Psychological Distress
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Valia PernidakiGoethe-University Frankfurt, Institute of Psychology, Frankfurt am Main, Germany.ORCID https://orcid.org/0009-0005-1433-0291
Karin Schermelleh-EngelGoethe-University Frankfurt, Institute of Psychology, Frankfurt am Main, Germany.ORCID https://orcid.org/0000-0002-6341-0803
Sarah SommerladGoethe-University Frankfurt, University Hospital Frankfurt, Department of Obstetrics and Perinatal Medicine, Frankfurt am Main, Germany.
Frank LouwenGoethe-University Frankfurt, University Hospital Frankfurt, Department of Obstetrics and Perinatal Medicine, Frankfurt am Main, Germany.
Silvia Oddo-SommerfeldGoethe-University Frankfurt, University Hospital Frankfurt, Department of Obstetrics and Perinatal Medicine, Frankfurt am Main, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile it is established that preterm birth (PB) increases the risk of psychological distress in fathers postpartum, the impact of a threatened PB on peripartum depressive and anxiety symptoms, as well as their course over time, remains insufficiently studied.

methodsWe assessed 116 men during their partner's pregnancy (T1) and 6 weeks postpartum (T2), using the Edinburgh Postnatal Depression Scale and the State-Trait Anxiety-Depression Inventory. Participants were categorized into a control group (CG) with term birth and two risk groups based on PB occurrence: 33 men with partners at risk of PB who had a term birth (RG-TB), and 38 men with partners at risk of PB who experienced a PB (RG-PB). Psychological distress was analyzed using multi-sample latent growth curve modeling.

resultsDuring pregnancy, psychological distress varied across groups: fathers in the RG-PB had elevated levels of depression and anxiety compared to the CG, while the RG-TB presented only weak evidence of heightened depressive but not anxiety symptoms. Notably, both risk groups had higher rates of elevated depressive symptoms than the CG. Postpartum, depressive symptoms did not differ between groups. However, fathers in the RG-PB had higher anxiety scores than fathers in the CG. Although trajectory analyses revealed no distinct group-specific patterns, the RG-TB consistently showed intermediate levels of distress between RG-PB and CG.

conclusionThreatened PB is associated with increased prenatal psychological distress in fathers, regardless of birth outcome. The combination of threatened and actual PB is linked to persistently elevated anxiety symptoms postpartum. CLINICAL RELEVANCE: Threatened PB identifies fathers at risk for psychological distress, warranting antenatal and follow-up screening, particularly due to persistent anxiety after PB. Fathers experiencing threatened PB followed by term birth remain vulnerable, as antenatal and postpartum emotional distress suggest the need for continued postpartum screening.

trial registrationClinicalTrials.gov: NCT01974531.

Indexed as

AnxietyDepressionFathersPeripartum PeriodPremature BirthAdultFemaleHumansMalePostpartum PeriodPregnancyRisk FactorsStress, Psychological

Identifiers

PMID42715170
PMCPMC13557346

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.