Evidence map›Paper›PMID 42714662›Full record

SynthesisHernia : the journal of hernias and abdominal wall surgery2026

Minimally invasive versus open abdominoperineal resection and the risk of postoperative perineal hernia: a systematic review and meta-analysis.

Beatriz Yukari Yokoyama, Victória Recidivi E Silva, Lucas Carvalho Lemos de Souza Aguiar, Hélder Santos Gonçalves, Lucas Monteiro Delgado, Claudia Theis, Sérgio Mazzola Poli de Figueiredo, Fernanda Bellotti Formiga, Bernardo Fontel Pompeu

Abstract readSystematic ReviewMeta-AnalysisComparative Study
In one paragraph

Synthesis in Hernia : the journal of hernias and abdominal wall surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Beatriz Yukari YokoyamaDepartment of Surgery, Heliopolis Hospital, São Paulo, SP, Brazil.ORCID http://orcid.org/0009-0002-7736-0816
Victória Recidivi E SilvaDepartment of Surgery, Heliopolis Hospital, São Paulo, SP, Brazil.ORCID http://orcid.org/0009-0001-5153-8412
Lucas Carvalho Lemos de Souza AguiarDepartment of Surgery, Heliopolis Hospital, São Paulo, SP, Brazil.ORCID http://orcid.org/0009-0009-6270-551X
Hélder Santos GonçalvesDepartment of Surgery, Heliopolis Hospital, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-5766-771X
Lucas Monteiro DelgadoFederal University of Minas Gerais, Belo Horizonte, Brazil.ORCID http://orcid.org/0009-0001-7687-3073
Claudia TheisDepartment of Surgery, University of North Carolina, Chapel Hill, NC, United States.ORCID http://orcid.org/0000-0002-1303-298X
Sérgio Mazzola Poli de FigueiredoDepartment of Surgery, University of North Carolina, Chapel Hill, NC, United States.ORCID http://orcid.org/0000-0003-2986-8164
Fernanda Bellotti FormigaDepartment of Surgery, Heliopolis Hospital, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-7225-7145
Bernardo Fontel PompeuDepartment of Surgery, Heliopolis Hospital, São Paulo, SP, Brazil. bernardo.pompeu@online.uscs.edu.br.ORCID http://orcid.org/0009-0009-2960-3810

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe impact of minimally invasive surgery on the risk of postoperative perineal hernia after abdominoperineal resection (APR) or extralevator abdominoperineal excision (ELAPE) remains uncertain. This study compares perineal hernia rates and perioperative outcomes between minimally invasive and open approaches.

methodsPubMed, Scopus, Web of Science, and Cochrane Library were searched through June 2026. Pooled odds ratios (ORs) and mean differences (MDs) with 95% confidence intervals (CIs) were calculated using random-effects models. A Bayesian meta-analysis was additionally performed for the primary outcome.

resultsFour comparative observational studies involving 763 patients were included; 249 underwent minimally invasive APR/ELAPE, and 514 underwent open APR/ELAPE. Postoperative perineal hernia was significantly more frequent following minimally invasive surgery (OR 4.13; 95% CI 2.24-7.61; p < 0.001). Intraoperative blood loss was significantly lower in the minimally invasive group (MD - 156.5 mL; 95% CI - 298.4 to - 14.5; p = 0.03), as was operative time (MD - 41.7 min; 95% CI - 60.8 to - 22.5; p < 0.01). No significant differences were observed in hospital stay (MD - 2.5 days; 95% CI - 5.4 to 0.4; p = 0.09) or 30-day readmission rates (OR 1.41; 95% CI 0.82-2.42; p = 0.209). Bayesian analysis yielded a posterior mean OR of 4.04 (95% CrI 1.96-8.36), corresponding to a 99.9% posterior probability that minimally invasive surgery increases the risk of postoperative perineal hernia.

conclusionMinimally invasive APR/ELAPE was associated with an increased risk of postoperative perineal hernia compared with the open approach. Strategies to reduce this complication while preserving the benefits of minimally invasive surgery warrant further investigation.

Indexed as

HerniaIncisional HerniaMinimally Invasive Surgical ProceduresPerineumPostoperative ComplicationsProctectomyHumansAbdominoperineal resectionExtralevator abdominoperineal excisionMeta-analysisMinimally invasive surgeryPerineal herniaRectal cancer

Identifiers

PMID42714662
PMCPMC13558427

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.