Evidence map›Paper›PMID 42714610›Full record

ArticleMolecular genetics and genomics : MGG2026

ACE2 and Parkinsonism‑related bone metabolic alterations: signaling pathways and hub gene analysis.

Tingting Liu, Yuheng Ren, Xinghua Tian, Jianshe Wei

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular genetics and genomics : MGG, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tingting Liu *Institute for Brain Sciences Research, School of Life Sciences, Henan University, Kaifeng, 475004, China.
Yuheng Ren *Institute for Brain Sciences Research, School of Life Sciences, Henan University, Kaifeng, 475004, China.
Xinghua TianInstitute for Brain Sciences Research, School of Life Sciences, Henan University, Kaifeng, 475004, China. tianxh@henu.edu.cn.
Jianshe WeiInstitute for Brain Sciences Research, School of Life Sciences, Henan University, Kaifeng, 475004, China. jswei@henu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical co-occurrence of Parkinson's disease (PD) and age-related bone loss in elderly patients has garnered increasing attention, yet its molecular mechanisms remain incompletely elucidated. This study used an 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced PD model in Ace2

Indexed as

Parkinsonian DisordersPeptidyl-Dipeptidase AAngiotensin-Converting Enzyme 2AnimalsBone and BonesBrainDisease Models, AnimalDopaminergic NeuronsGene Expression ProfilingGene Regulatory NetworksMaleMiceSignal TransductionAce2 protein, mouseAngiotensin-Converting Enzyme 2Peptidyl-Dipeptidase AACE2Bone brain axisBone metabolismMolecular mechanismParkinson's disease

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.