Evidence map›Paper›PMID 42714603›Full record

ArticlePediatric surgery international2026

Evaluation of diagnostic indicators using normalized CT attenuation values of the ovarian wall in contrast-enhanced CT for pediatric ovarian tumor torsion.

Michiko Ueda, Naonori Kawakubo, Junnosuke Maniwa, Yukihiro Toriigahara, Takuya Kondo, Yoshiaki Takahashi, Atsuhisa Fukuta, Koichiro Yoshimaru, Kouji Nagata, Junko Miyata and 2 more

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Article in Pediatric surgery international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Michiko UedaDepartment of Pediatric Surgery, Faculty of Medical Science,, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Naonori KawakuboDepartment of Pediatric Surgery, Faculty of Medical Science,, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan. kawakubo.naonori.061@m.kyushu-u.ac.jp.
Junnosuke ManiwaDepartment of Pediatric Surgery, Faculty of Medical Science,, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Yukihiro ToriigaharaDepartment of Pediatric Surgery, Faculty of Medical Science,, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Takuya KondoDepartment of Pediatric Surgery, Faculty of Medical Science,, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Yoshiaki TakahashiDepartment of Pediatric Surgery, Faculty of Medical Science,, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Atsuhisa FukutaDepartment of Pediatric Surgery, Faculty of Medical Science,, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Koichiro YoshimaruDepartment of Pediatric Surgery, Faculty of Medical Science,, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Kouji NagataDepartment of Pediatric Surgery, Faculty of Medical Science,, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Junko MiyataDepartment of Pediatric Surgery, Faculty of Medical Science,, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Toshiharu MatsuuraDepartment of Pediatric Surgery, Faculty of Medical Science,, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Tatsuro TajiriDepartment of Pediatric Surgery, Faculty of Medical Science,, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePediatric ovarian tumor torsion often presents with nonspecific symptoms, and delayed diagnosis can lead to ovarian necrosis. Although contrast-enhanced CT is frequently used, objective quantitative indicators have not been established. This study evaluated normalized ovarian wall CT attenuation (n-OWA) and a combined index incorporating white blood cell count (WBC).

methodsAmong 82 patients with surgically-treated ovarian tumor, 52 who underwent contrast-enhanced CT (15 with torsion and 37 without torsion) were analyzed. The n-OWA was calculated as the ovarian wall CT attenuation divided by the inferior vena cava attenuation. The WBC/n-OWA ratio was also evaluated. Group comparisons were performed using the Wilcoxon test, and diagnostic performance was evaluated by an ROC analysis.

resultsThe n-OWA was significantly lower in the torsion group (0.25 vs. 0.31, p = 0.02), with an AUC of 0.71. The WBC/n-OWA ratio was significantly higher in the torsion group (44.8 vs. 19.9, p < 0.01) and showed improved diagnostic performance with an AUC of 0.86. At a cutoff of 25.4, the sensitivity and specificity were 1.00 and 0.70, respectively.

conclusionsThe n-OWA is an objective imaging biomarker for pediatric ovarian torsion. The WBC/n-OWA ratio may further improve diagnostic accuracy, particularly for excluding ovarian torsion.

Indexed as

Ovarian NeoplasmsOvarian TorsionOvaryTomography, X-Ray ComputedAdolescentChildChild, PreschoolContrast MediaFemaleHumansLeukocyte CountRetrospective StudiesROC CurveSensitivity and SpecificityContrast MediaContrast-enhanced computed tomographyDiagnostic biomarkerNormalized CT attenuationOvarian ischemiaPediatric ovarian tumor torsionROC analysis

Identifiers

PMID42714603

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