Evidence map›Paper›PMID 42714317›Full record

ArticleOral health & preventive dentistry2026

Fluoride Toothpaste Market Surveillance in the Dominican Republic: Quality Gaps and Policy Implications.

Ninoska Abreu-Placeres, Luis Eduardo Garrido, Frank Lippert, Kim Rud Ekstrand, George Eckert, Guillermo Tamayo-Cabeza, Stefania Martignon, Esperanza Angeles Martinez-Mier

Abstract read
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Article in Oral health & preventive dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Ninoska Abreu-Placeres
Luis Eduardo Garrido
Frank Lippert
Kim Rud Ekstrand
George Eckert
Guillermo Tamayo-Cabeza
Stefania Martignon
Esperanza Angeles Martinez-Mier

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe objective was to determine whether toothpastes marketed across the Dominican Republic provide fluoride levels that consistently meet internationally recommended benchmarks for caries prevention. METHODS AND MATERIALS: A total of 22 toothpaste products representing 11 brands were sampled from four of the country's most populated provinces. Six tubes per toothpaste were analysed using standardised fluoride measurement protocols. Total soluble fluoride (TSF) concentrations were evaluated against two internationally recognised benchmarks: ≥ 90% of labelled content and the 1000 ppm threshold for effective caries prevention. The proportion of toothpastes meeting these benchmarks was calculated, and Welch's ANOVAs assessed regional variability in TSF.

resultsResults showed that while 68.2% of toothpastes met both fluoride benchmarks, 31.8% failed to do so by containing insufficient TSF relative to labelled content, falling below the 1000-ppm threshold, or both. Toothpastes with sodium monofluorophosphate (SMFP) exhibited the highest non-soluble fluoride levels, averaging up to 44.1%. Significant variability in TSF concentrations was observed across provinces, with Greater Santo Domingo consistently showing lower TSF levels than other regions. Locally manufactured toothpastes and products with incompatible abrasives demonstrated the greatest fluoride losses.

conclusionsOur findings provide market-wide surveillance evidence from a low- and middle-income country directly supporting WHO's Global Oral Health Action Plan (2023-2030). They highlight quality assurance gaps in fluoride toothpaste that undermine population-level caries prevention. These results underscore the global need for routine market monitoring, ISO-concordant standards, and fiscal policies to ensure effective, affordable fluoride toothpaste is reliably available worldwide.

Indexed as

Cariostatic AgentsFluoridesHealth PolicyToothpastesDental CariesDominican RepublicFluoride TreatmentHumansCariostatic AgentsFluoridesToothpastesdental cariesDominican Republicfluoridestoothpastes

Identifiers

PMID42714317
PMCPMC13559059

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.