Evidence map›Paper›PMID 42713878›Full record

ReviewMicrobiologyOpen2026

Gastrointestinal Microbiome Dysbiosis in Cancer Development: Mechanisms and Biomarker Potential.

Negar Asgari, Mehrasa Asghari, Touraj Farazmandfar

Abstract readReview
In one paragraph

Review in MicrobiologyOpen, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Negar AsgariInstitute of Regenerative Medicine and Biotherapy, Université de Montpellier, CHU de Montpellier, Montpellier, France.ORCID https://orcid.org/0000-0002-0595-1089
Mehrasa AsghariMedical Cellular and Molecular Research Center, Biomedical Research Institute, Golestan University of Medical Sciences, Gorgan, Iran.ORCID https://orcid.org/0000-0002-9179-391X
Touraj FarazmandfarMedical Cellular and Molecular Research Center, Biomedical Research Institute, Golestan University of Medical Sciences, Gorgan, Iran.ORCID https://orcid.org/0000-0002-8207-6572

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increasing evidence indicates that alterations in the gastrointestinal microbiota are associated with the initiation and progression of gastrointestinal cancers. Abundant evidence suggests that gastrointestinal microbiota dysbiosis plays an important role in the development of gastrointestinal cancers by producing proinflammatory and immunosuppressive signals. This review examines the role of microbiome dysbiosis in the pathogenesis of gastrointestinal malignancies. The composition of the microbiota varies greatly among individuals and depends on various factors such as age, diet, lifestyle, genetics, medications, and environmental factors. Given this diversity, a comprehensive characterization of the gastrointestinal microbiota is crucial to elucidate its role in carcinogenesis. Therefore, investigating the microbial composition of the host gastrointestinal tract can provide important information about the status of gastrointestinal cancers.

Indexed as

DysbiosisGastrointestinal MicrobiomeGastrointestinal NeoplasmsAnimalsBiomarkersCarcinogenesisHumansBiomarkerscarcinogenesisdysbiosisgastrointestinal cancermicrobiome

Identifiers

PMID42713878
PMCPMC13555811

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.