Evidence map›Paper›PMID 42713435›Full record

ArticleGastroenterology & hepatology2026

Sleep and Disorders of Gut-Brain Interaction.

Brian E Lacy, Jessica C Petrov, Pablo R Castillo

Abstract read
In one paragraph

Article in Gastroenterology & hepatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Brian E LacyDivision of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida.
Jessica C PetrovDivision of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida.
Pablo R CastilloDivision of Sleep Medicine, Mayo Clinic, Jacksonville, Florida.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sleep plays a critical role in maintaining good physical and emotional health. Sleep and circadian rhythms are fundamental regulators of human physiology, influencing most biological processes from the cellular to the organ-system level. Sleep disorders are common with a prevalence of 30% in adults. Impaired sleep reduces patients' quality of life and has a significant negative economic impact on the health care system. Sleep deprivation can affect the brain and alter normal circadian rhythms. These disturbances influence the brain-gut axis and subsequently affect both symptom development and symptom expression in patients with disorders of gut-brain interaction (DGBIs), including functional dyspepsia and irritable bowel syndrome. DGBIs are highly prevalent with at least 40% of adults worldwide meeting criteria for at least 1 DGBI. This article reviews the prevalence and impact of disordered sleep, discusses the basics of normal and abnormal sleep, examines the role of diagnostic testing for sleep disorders, and evaluates the role of disordered sleep in common DGBIs. Practical tips to evaluate and treat patients with DGBIs and disordered sleep are also discussed.

Indexed as

disorders of gut-brain interactionfunctional dyspepsiainsomniairritable bowel syndromeSleepsleep disorders

Identifiers

PMID42713435
PMCPMC13552402

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.