Evidence map›Paper›PMID 42713342›Full record

ArticleOxford medical case reports2026

Co-amoxicillin-induced reactivation of auto-brewery syndrome in a patient treated for community acquired pneumonia: a clinical case report.

Philipp Widmer, Flavia A Miesch, Barbara Scotti, Gian Erni, Roland Sperb

Abstract readCase Reports
In one paragraph

Article in Oxford medical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Philipp WidmerDepartment of Internal Medicine, Luzerner Kantonsspital, Spitalstrasse 16A, Sursee 6210, Switzerland.ORCID https://orcid.org/0009-0009-4824-0605
Flavia A MieschDepartment of General Surgery, Luzerner Kantonsspital, Spitalstrasse 16A, Sursee 6210, Switzerland.ORCID https://orcid.org/0009-0009-5255-7955
Barbara ScottiDepartment of Emergency Medicine, Luzerner Kantonsspital, Spitalstrasse 16A, Sursee 6210, Switzerland.ORCID https://orcid.org/0000-0003-2570-6432
Gian ErniDepartment of Emergency Medicine, Luzerner Kantonsspital, Spitalstrasse 16A, Sursee 6210, Switzerland.
Roland SperbDepartment of Internal Medicine, Luzerner Kantonsspital, Spitalstrasse 16A, Sursee 6210, Switzerland.ORCID https://orcid.org/0000-0002-4744-0682

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Auto-Brewery Syndrome (ABS) is a rare metabolic condition characterized by endogenous ethanol production through fermentation of ingested carbohydrates by intestinal microorganisms. Clinical manifestations resemble alcohol intoxication, including ataxia, dysarthria, gastrointestinal symptoms, and altered mental status, despite the absence of alcohol intake. We report a case of a patient in his mid-40s who developed ABS reactivation following treatment with Amoxicillin/Clavulanic acid for community-acquired pneumonia. The patient was successfully managed with targeted antimicrobial therapy, dietary carbohydrate restriction, and probiotic supplementation, resulting in clinical improvement. This case highlights a rare instance of antibiotic-associated ABS relapse and underscores the diagnostic challenge of this unrecognized microbial condition.

Indexed as

acute alcohol intoxicationamoxicillin/clavulanic acidantibiotic-induced Dysbiosisauto-brewery syndromeCo-amoxicillingut fermentation syndrome

Identifiers

PMID42713342
PMCPMC13553005

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.