Evidence map›Paper›PMID 42713280›Full record

ReviewFederal practitioner : for the health care professionals of the VA, DoD, and PHS2026

Optimizing Care for Veterans at Risk of Cancer From Camp Lejeune Water Exposure.

Christi A Blake, Kirsten N Brondstater

Abstract readReview
In one paragraph

Review in Federal practitioner : for the health care professionals of the VA, DoD, and PHS, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Christi A BlakeShenandoah University Doctor of Medical Science Program, Winchester, Virginia.
Kirsten N BrondstaterShenandoah University Doctor of Medical Science Program, Winchester, Virginia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: From 1953 to 1985, as many as 1 million Marines, Navy personnel, civilian workers, and their families stationed at Camp Lejeune were exposed to volatile organic compounds (VOCs) through contaminated drinking and bathing water. Epidemiologic studies link VOC exposure to ≥ 10 cancers. Cohort studies have shown higher cancer incidence and mortality among Camp Lejeune personnel, with up to a 3- to 6-fold increase for some cancers compared with Camp Pendleton controls. Clinical awareness of cancers associated with Camp Lejeune water contamination remains limited. Federal primary care and internal medicine clinicians are uniquely positioned to address this gap. Observations: Camp Lejeune VOC exposure is associated with solid tumor and hematologic cancers, which present with various symptoms, examination findings, and diagnostic considerations. Primary care and internal medicine clinicians can improve outcomes by recognizing symptom patterns, conducting thorough physical examinations, and implementing a targeted diagnostic screening panel for identified veterans who were stationed at Camp Lejeune. A proposed panel includes complete blood count with differential and peripheral smear, comprehensive metabolic panel, lactate dehydrogenase, urinalysis, low-dose chest computed tomography (CT), and CT of the abdomen and pelvis. Educating veterans and clinicians on symptom recognition, relevant physical examination findings, and the value of initial screening may help close this critical gap and reduce costs associated with advanced-stage cancer treatment. Conclusion: Clinicians caring for veterans exposed to Camp Lejeune VOCs can improve outcomes and quality of life through increased awareness of exposure-associated symptoms, targeted physical examination, and timely use of cost-effective screening to support earlier cancer detection and reduce diagnostic delays and costs. Clinicians are central to early recognition, physical assessment, appropriate screening tools, and ongoing care for this high-risk veteran cohort.

Identifiers

PMID42713280
PMCPMC13552690

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.