Evidence map›Paper›PMID 42713227›Full record

ArticleRSC advances2026

Novel bis(benzylidene)-6-methyl-2-thiouracil derivatives: design, synthesis, and molecular docking as potential antimicrobial agents against multidrug-resistant pathogenic bacteria.

Mai Thabet, Ahmed A El-Rashedy, Hossam M El-Masry, Ahmed A El-Sayed, Shaker Youssif, Samar Elkalyoubi, Wael Shehta

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mai ThabetChemistry Department, Faculty of Science, Zagazig University 44519 Zagazig Egypt syoussif@hotmail.com syoussif@zu.edu.eg.
Ahmed A El-RashedyNatural and Microbial Products Department, Pharmaceutical and Drug Industries Research Institute, National Research Center (NRC) Dokki 12622 Giza Egypt.ORCID https://orcid.org/0000-0003-3899-5376
Hossam M El-MasryChemistry of Natural and Microbial Products Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre Dokki 12622 Giza Egypt.ORCID https://orcid.org/0000-0002-5473-8081
Ahmed A El-SayedPhotochemistry Department, Chemical Industries Research Institute, National Research Centre Dokki 12622 Giza Egypt.ORCID https://orcid.org/0000-0003-2555-5259
Shaker YoussifChemistry Department, Faculty of Science, Zagazig University 44519 Zagazig Egypt syoussif@hotmail.com syoussif@zu.edu.eg.ORCID https://orcid.org/0000-0003-2623-0261
Samar ElkalyoubiPharmaceutical Organic Chemistry, Faculty of Pharmacy, Port Said University Port Said 42511 Egypt.ORCID https://orcid.org/0000-0002-4648-5184
Wael ShehtaChemistry Department, Faculty of Science, Zagazig University 44519 Zagazig Egypt syoussif@hotmail.com syoussif@zu.edu.eg.ORCID https://orcid.org/0000-0002-6522-7279

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pyrimidine-based heterocycles are crucial scaffolds in medicinal chemistry due to their extensive biological activity. This study involved the condensation of 6-methyl-2-thiouracil with various aromatic aldehydes under reflux in acetic and hydrochloric acid, resulting in the synthesis of a novel series of bis(benzylidene)-6-methyl-2-thiouracil derivatives (2a-e). IR,

Identifiers

PMID42713227
PMCPMC13551430

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.