Evidence map›Paper›PMID 42713014›Full record

ArticleiScience2026

Early life high-fat diet exposure modulates adult metabolic phenotypes in

Prachi Mishra, Gaurav Yadav, Shrishti Mitra, Raunak Gupta, Ranjan Kumar Sahu, Rogers Koboji, Kashyap Kumar Dubey, Ranjan Kumar Nanda, Vijendra Sharma, Pawel Michalak and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Prachi MishraDepartment of Biochemistry, University of Delhi South Campus, New Delhi 110021, India.
Gaurav YadavDepartment of Biochemistry, University of Delhi South Campus, New Delhi 110021, India.
Shrishti MitraDepartment of Biochemistry, University of Delhi South Campus, New Delhi 110021, India.
Raunak GuptaDepartment of Biochemistry, University of Delhi South Campus, New Delhi 110021, India.
Ranjan Kumar SahuDepartment of Neurology, Houston Methodist Research Institute, Houston, TX 77030, USA.
Rogers KobojiDepartment of Biomedical Sciences, University of Windsor, Windsor, Ontario N9B 3P4, Canada.
Kashyap Kumar DubeySchool of Biotechnology, Jawaharlal Nehru University, New Delhi 110067, India.
Ranjan Kumar NandaTranslational Health Group, International Centre for Genetic Engineering and Biotechnology (ICGEB), New Delhi 110067, India.
Vijendra SharmaDepartment of Biomedical Sciences, University of Windsor, Windsor, Ontario N9B 3P4, Canada.
Pawel MichalakInstitute of Evolution, University of Haifa, Haifa 31905, Israel.
Dau Dayal AggarwalDepartment of Biochemistry, University of Delhi South Campus, New Delhi 110021, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early-life exposure to dietary excess of lipids increases lifelong vulnerability to metabolic dysfunction, but the determinants of this susceptibility remain unclear. Here, we combine paired-tissue transcriptomics (whole head and fat body), metabolomics, and gut microbiota profiling in

Indexed as

drosophila melanogasterearly-life nutritiongut microbiotahigh-fat dietmitochondrial dysfunctionmulti-omics

Identifiers

PMID42713014
PMCPMC13551879

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.