Evidence map›Paper›PMID 42712917›Full record

ArticleBrain communications2026

Induced epileptic seizures in larval zebrafish reveal a synaptic modulation associated with the post-ictal state.

Dor Meron, Yarden Levinsky, Milagros Prendes, Inbar Brosh, Moti Freiman, Limor Freifeld

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Article in Brain communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dor MeronBiomedical Engineering Department, Technion-Israel Institute of Technology, Haifa 32000, Israel.
Yarden LevinskyBiomedical Engineering Department, Technion-Israel Institute of Technology, Haifa 32000, Israel.
Milagros PrendesBiomedical Engineering Department, Technion-Israel Institute of Technology, Haifa 32000, Israel.
Inbar BroshBiomedical Engineering Department, Technion-Israel Institute of Technology, Haifa 32000, Israel.
Moti FreimanBiomedical Engineering Department, Technion-Israel Institute of Technology, Haifa 32000, Israel.
Limor FreifeldBiomedical Engineering Department, Technion-Israel Institute of Technology, Haifa 32000, Israel.ORCID https://orcid.org/0000-0002-0739-6947

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epilepsy patients suffer from spontaneous and recurrent seizures. In some cases, after seizures, a transient post-ictal state associated with cognitive deficits develops. Moreover, seizure-induced alterations in brain structure and function may give rise to neurological comorbidities associated with epilepsy. Nevertheless, the mechanisms underlying neurological comorbidities in epilepsy broadly and the post-ictal state specifically are not well understood. Here we used a well-established model of acutely induced seizures in larval zebrafish to reveal how seizures modulate a neural circuit implementing a specific sensorimotor transformation, the escape response. Using

Indexed as

epilepsyexpansion microscopyglycinergic synapseslarval zebrafishneural activity imaging

Identifiers

PMID42712917
PMCPMC13550772

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.