Evidence map›Paper›PMID 42712814›Full record

ArticleInternational journal of microbiology2026

Complete Genome Sequencing of Occult Hepatitis B Virus in Hemodialysis Patients Reveals Subgenotype D2 and Immune Escape Mutations in Bangladesh.

Roni Mia, Anandha Mozumder, Parsa Irin Disha, Nashid Sultana Ishi, S M Nazmul Hasan, Anupam Das, Chirojit Debnath, M Shaminur Rahman, Sharmin Akter, S M Rashed Ul Islam and 5 more

Abstract read
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In one paragraph

Article in International journal of microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Roni MiaDepartment of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh, bau.edu.bd.ORCID https://orcid.org/0009-0008-5536-5417
Anandha MozumderDepartment of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh, bau.edu.bd.ORCID https://orcid.org/0009-0006-3125-0100
Parsa Irin DishaDepartment of Microbiology, Mymensingh Medical College, Mymensingh, Bangladesh, mmc.gov.bd.
Nashid Sultana IshiDepartment of Microbiology, Mymensingh Medical College, Mymensingh, Bangladesh, mmc.gov.bd.
S M Nazmul HasanDepartment of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh, bau.edu.bd.ORCID https://orcid.org/0009-0004-0863-4048
Anupam DasDepartment of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh, bau.edu.bd.ORCID https://orcid.org/0009-0008-4507-9089
Chirojit DebnathDepartment of Hepatology, Mymensingh Medical College, Mymensingh, Bangladesh, mmc.gov.bd.
M Shaminur RahmanDepartment of Microbiology, Jashore University of Science and Technology, Jashore, Bangladesh, just.edu.bd.
Sharmin AkterDepartment of Physiology, Bangladesh Agricultural University, Mymensingh, Bangladesh, bau.edu.bd.ORCID https://orcid.org/0000-0001-6901-3377
S M Rashed Ul IslamDepartment of Virology, Bangladesh Medical University, Dhaka, Bangladesh.ORCID https://orcid.org/0000-0002-8164-5905
Sukumar SahaDepartment of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh, bau.edu.bd.ORCID https://orcid.org/0000-0002-8036-0190
Tofazzal IslamInstitute of Biotechnology and Genetic Engineering, Gazipur Agricultural University, Gazipur, Bangladesh.ORCID https://orcid.org/0000-0002-7613-0261
Muzahed Uddin AhmedDepartment of Medicine, Bangladesh Agricultural University, Mymensingh, Bangladesh, bau.edu.bd.
Chitta Ranjan DebnathDepartment of Hepatology, Mymensingh Medical College, Mymensingh, Bangladesh, mmc.gov.bd.
Md Golzar HossainDepartment of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh, bau.edu.bd.ORCID https://orcid.org/0000-0002-1487-5444

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis B virus (HBV) remains a major global health concern, and occult HBV infection (OBI) presents significant diagnostic and clinical challenges, particularly among hemodialysis (HD) patients. This study is aimed at characterizing complete HBV genomes from maintenance HD patients with OBI in Bangladesh to elucidate genetic features, mutational patterns, and clinical implications. Serum samples from two HBsAg-negative HD patients were screened by ELISA and quantitative PCR. Viral DNA was amplified by PCR across four overlapping open reading frames (ORFs) and sequenced on the Illumina platform. Genome assembly, phylogenetic analysis, and mutational profiling were performed using reference datasets and bioinformatics tools. Antigenicity and hydrophilicity of HBsAg were predicted in silico. Both patients were anti-HBc and anti-HBs positive with high HBV DNA loads (2.29 × 10

Indexed as

HBV genome sequencinghemodialysis patientsmutational analysisoccult Hepatitis B infection (OBI)phylogeny

Identifiers

PMID42712814
PMCPMC13550878

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.