Evidence map›Paper›PMID 42712713›Full record

ArticleHealth science reports2026

Laboratory-Detected

Jiyun Hu, Fuxing Deng, Tingyue Hu, Binbin Meng, Songyun Deng, Lina Zhang, Wenchao Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiyun HuDepartment of Critical Care Medicine, Hunan Provincial Clinical Research Center for Critical Care Medicine, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital Central South University Changsha Hunan PR China.ORCID https://orcid.org/0000-0003-4154-2677
Fuxing DengDepartment of Critical Care Medicine, Hunan Provincial Clinical Research Center for Critical Care Medicine, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital Central South University Changsha Hunan PR China.ORCID https://orcid.org/0000-0002-5490-5695
Tingyue HuDepartment of Gastroenterology Lixian People's Hospital Lixian Hunan PR China.
Binbin MengDepartment of Critical Care Medicine, Hunan Provincial Clinical Research Center for Critical Care Medicine, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital Central South University Changsha Hunan PR China.
Songyun DengDepartment of Critical Care Medicine, Hunan Provincial Clinical Research Center for Critical Care Medicine, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital Central South University Changsha Hunan PR China.
Lina ZhangDepartment of Critical Care Medicine, Hunan Provincial Clinical Research Center for Critical Care Medicine, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital Central South University Changsha Hunan PR China.
Wenchao LiDepartment of Critical Care Medicine, Hunan Provincial Clinical Research Center for Critical Care Medicine, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital Central South University Changsha Hunan PR China.ORCID https://orcid.org/0009-0008-8882-945X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Sepsis disrupts intestinal microbiota, and broad-spectrum antibiotics may worsen dysbiosis. Methods: We retrospectively analyzed 13,484 adult sepsis hospitalizations from MIMIC-IV. The exposure was any laboratory-detected C. difficile-positive stool test during the index hospitalization. Cox regression, detailed early-antibiotic adjustment, stabilized inverse probability weighting, timing- and assay-based sensitivity analyses, and a post hoc nested-model comparison assessed association and incremental prediction. Archived positive-subgroup machine-learning models were retained as exploratory risk-stratification analyses. Results: Detailed early-antibiotic adjustment substantially attenuated the association: the 30-day hazard ratio (HR) was 0.98 (95% CI, 0.87-1.11; Conclusions: While laboratory-detected

Indexed as

Clostridioides difficilemarkerprognosissepsisstool pathogens

Identifiers

PMID42712713
PMCPMC13550520

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.