ArticleFrontiers in plant science2026
Exogenous γ-aminobutyric acid mitigates physiological and transcriptomic responses of
Article in Frontiers in plant science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Methods: In this study, seedlings were subjected to alkali salt, cadmium, and combined stress treatments, followed by foliar application of GABA. Germination, growth, physiological traits, and transcriptomic responses were analyzed using an integrated multi-level approach. Results: The alkali salt, cadmium, and combined alkali salt and cadmium stress significantly inhibited germination and growth, with combined stress showing the strongest effects. Stress induced reactive oxygen species accumulation, lipid peroxidation, and photosynthetic inhibition. Exogenous γ-aminobutyric acid alleviated these effects by improving germination, growth, chlorophyll content, and root activity, while reducing oxidative damage. It enhanced osmotic adjustment via increased proline and soluble sugars and strengthened antioxidant enzyme activities, including superoxide dismutase, peroxidase, catalase, ascorbate peroxidase, and glutathione reductase, restoring redox homeostasis. Discussion: Transcriptome analysis showed that GABA reprogrammed stress-responsive genes enriched in "MAPK signaling pathway-plant", "Plant hormone signal transduction", "Plant-pathogen interaction", "Peroxisome", and "Glutathione metabolism" pathways. Gene set enrichment analysis further indicated recovery of photosynthesis, carbon metabolism, and primary "metabolic process", suggesting restoration of energy balance and metabolic homeostasis. Collectively, GABA functions as a multi-level regulator integrating redox balance, signaling pathways, and metabolic reprogramming to enhance stress tolerance in
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.