Evidence map›Paper›PMID 42712434›Full record

ArticleFrontiers in neurology2026

Exploring the research landscape of exosomes in Parkinson's disease: a bibliometric analysis.

Yuqi Liu, Yun Liu, Yujie Li, Yujie Wang, Jianhui Liu

Abstract read
In one paragraph

Article in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuqi Liu *The Sixth Hospital of Guiyang, Guiyang, China.
Yun Liu *School of Basic Medical Sciences, Zhejiang Chinese Medicine University, Hangzhou, China.
Yujie LiThe First Clinical Medical College of Guizhou University of Traditional Chinese Medicine, Guiyang, China.
Yujie WangWeng'an County People's Hospital, Weng'an, Guizhou, China.
Jianhui LiuDepartment of Neurology, The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Parkinson's disease (PD) is characterized by progressive loss of dopaminergic neurons in the substantia nigra and pathological aggregation of Methods: Original articles and reviews published between January 1, 2005 and December 31, 2025 were retrieved from the Web of Science Core Collection (WoSCC) and Scopus; 1,486 publications were included after merging and deduplication. CiteSpace, VOSviewer, Bibliometrix, and Microsoft Excel were used for bibliometric and visualization analyses, covering publication output, contributing countries and institutions, authors, journals, citation counts, and keyword trends. Results: PD-related exosome research spanned 63 countries, with publication output accelerating markedly after 2019 and peaking in 2023 (231 articles), accumulating 72,631 citations. China (427 articles, 28.7%) and the United States (238 articles, 16%) were the leading contributors, with the United States exhibiting a more prominent hub role in international collaboration networks. Taipei Medical University and Capital Medical University were among the most productive institutions; Zhang, Jing, and Shi, Min were among the most influential authors. Conclusion: PD-related exosome research is undergoing sustained expansion with an increasingly translational orientation, and its focus shifting from pathological mechanisms toward biofluid biomarker development and engineered exosome-based delivery strategies. Mapping this knowledge landscape facilitates identification of key teams and emerging directions, providing a reference for methodological standardization, multicenter clinical validation, and interdisciplinary collaboration to advance clinical translation.

Indexed as

BibliometricsBiomedical ResearchExosomesParkinson DiseaseAnimalsBiomarkersHumansBiomarkersbibliometric analysisbiomarkersexosomesParkinson’s diseaseresearch trends

Identifiers

PMID42712434
PMCPMC13549832

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.