Evidence map›Paper›PMID 42712408›Full record

ArticleFrontiers in network physiology2026

Generalized net modelling of the male urinary system with prostate-related outflow obstruction.

Martin Lubich, Krassimir Atanassov, Peter Vassilev, Vassia Atanassova, Chavdar Slavov, Elenko Popov, Lyudmila Todorova

Abstract read
In one paragraph

Article in Frontiers in network physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Martin LubichUniversity Hospital "Sofiamed", Sofia, Bulgaria.
Krassimir AtanassovDepartment of Bioinformatics and Mathematical Modelling, Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Sofia, Bulgaria.
Peter VassilevDepartment of Bioinformatics and Mathematical Modelling, Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Sofia, Bulgaria.
Vassia AtanassovaDepartment of Bioinformatics and Mathematical Modelling, Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Sofia, Bulgaria.
Chavdar SlavovFaculty of Medicine, Acibadem City Clinic Tokuda Univesity Hospital, Sofia, Bulgaria.
Elenko PopovMedical University Sofia, Sofia, Bulgaria.
Lyudmila TodorovaDepartment of Bioinformatics and Mathematical Modelling, Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Sofia, Bulgaria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present paper proposes a generalized net model of the male urinary system that reflects the principal anatomical and functional relations among the kidneys, ureters, urinary bladder, urethra, nervous system, muscle system, and prostate gland, both in norm and pathology. Particular attention is given to the role of the prostate gland and to changes in urinary flow and bladder emptying associated with prostate-related outflow obstruction. By representing material and informational flows and their interactions across several physiological subsystems, the model is conceptually aligned with the perspective of network physiology. The proposed framework provides a formal basis for the qualitative comparison of normal and pathological states and for future extension, parameterization, scenario-based simulation, and clinical validation.

Indexed as

generalized netshuman bodymathematical modellingnetwork physiologyprostate glandurinary system

Identifiers

PMID42712408
PMCPMC13549845

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.