Observational studyFrontiers in neurology2026
Tuina combined with pulsed dry cupping for constipation and gastrointestinal recovery in severe traumatic brain injury: a multidimensional rehabilitation study.
Observational study in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
Objective: To evaluate the efficacy of Tuina combined with pulsed dry cupping for constipation management and gastrointestinal (GI) function recovery in severe traumatic brain injury (sTBI), and its associations with nutritional status, neurological function, and patient satisfaction. Methods: This study was a prospective real-world observational cohort study. A total of 120 patients with severe traumatic brain injury (sTBI) were consecutively enrolled between March 2023 and March 2024. Patients were classified into routine care or combined intervention groups according to routine clinical care pathways without randomization or investigator-driven assignment. Participants in the combined intervention group received Tuina combined with pulsed dry cupping once daily, five times per week for 4 consecutive weeks. Outcomes included constipation-related measures, gastrointestinal function, nutritional indicators, neurological function, and patient-reported outcomes. Appropriate statistical methods were applied for comparisons. Results: Post-intervention, the combined intervention group showed increased completely spontaneous bowel movements, reduced defecation effort, higher BSS scores, and lower PAC-SYM and GSRS scores versus the routine care group ( Conclusion: In this prospective real-world observational cohort study, Tuina combined with pulsed dry cupping was associated with improvements in constipation-related symptoms, gastrointestinal function, nutritional indicators, and patient-reported outcomes in patients with severe traumatic brain injury. However, given the observational design, causal inferences regarding efficacy cannot be established.
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