Evidence map›Paper›PMID 42712219›Full record

ArticleJournal of separation science2026

UHPLC-Q/TOF-MS Characterization of Danshen-Chuanxiong and Mechanistic Insights Into Its Protective Effects Against Aβ

Hui Wang, Ling Li, Xiaoli He, Shuqi Shen, Liang Chao, Piaoxue You, Kaihong Ji, Yue Liu, Zhanying Hong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of separation science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hui Wang *School of Pharmacy, Naval Medical University, Shanghai, China.
Ling Li *School of Pharmacy, Naval Medical University, Shanghai, China.
Xiaoli HeSchool of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Shuqi ShenSchool of Pharmacy, Naval Medical University, Shanghai, China.
Liang ChaoSchool of Pharmacy, Naval Medical University, Shanghai, China.
Piaoxue YouSchool of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Kaihong JiFirst Affiliated Hospital of Naval Medical University, Naval Medical University, Shanghai, China.
Yue LiuSchool of Pharmacy, Naval Medical University, Shanghai, China.
Zhanying HongSchool of Pharmacy, Naval Medical University, Shanghai, China.

Funding

National Natural Science Foundation of China 82173777National Natural Science Foundation of China 82473885National Natural Science Foundation of China 82504742
6 · The paper itself

Abstract

Danshen-Chuanxiong is a traditional herb pair used for cardiovascular and cerebrovascular disorders, but its chemical basis and potential effects in Alzheimer's disease (AD)-related endothelial injury remain incompletely defined. Here, an integrated analytical workflow combining reversed-phase liquid chromatography (RPLC) and hydrophilic interaction liquid chromatography (HILIC) with quadrupole time-of-flight mass spectrometry (Q-TOF-MS), cellular assays, metabolomics, and network pharmacology was applied in an amyloid-β

Indexed as

Amyloid beta-PeptidesBrainDrugs, Chinese HerbalEndothelial CellsMetabolomicsPeptide FragmentsCell SurvivalChromatography, High Pressure LiquidHumansMass SpectrometrySalvia miltiorrhizaAmyloid beta-Peptidesamyloid beta-protein (1-42)Drugs, Chinese HerbalPeptide FragmentsAβ1‐42brain endothelial cellscellular metabolomicsdanshen–chuanxiongRPLC/HILICUHPLC‐Q/TOF‐MS

Identifiers

PMID42712219
PMCPMC13555308

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.