Evidence map›Paper›PMID 42711687›Full record

ArticleTrends in hearing

The Effect of Etiology, Array Type and Duration of Deafness on Focused Detection Thresholds in Cochlear Implant Listeners.

Caylin McCallick, Scott C Aker, Heather A Kreft, Tina Munjal, Andrew J Oxenham, Julie G Arenberg

Abstract readComparative Study
In one paragraph

Article in Trends in hearing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Caylin McCallickMassachusetts Eye and Ear, Harvard Medical School, Department of Otolaryngology Head and Neck Surgery, Boston, MA, USA.ORCID 0009-0003-5925-7994
Scott C AkerMassachusetts Eye and Ear, Harvard Medical School, Department of Otolaryngology Head and Neck Surgery, Boston, MA, USA.ORCID 0000-0002-2573-3193
Heather A KreftDepartment of Psychology, University of Minnesota, Minneapolis, MN, USA.ORCID 0000-0003-0764-0820
Tina MunjalMassachusetts Eye and Ear, Harvard Medical School, Department of Otolaryngology Head and Neck Surgery, Boston, MA, USA.
Andrew J OxenhamDepartment of Psychology, University of Minnesota, Minneapolis, MN, USA.ORCID 0000-0002-9365-1157
Julie G ArenbergMassachusetts Eye and Ear, Harvard Medical School, Department of Otolaryngology Head and Neck Surgery, Boston, MA, USA.ORCID 0000-0002-5511-211X

Funding

Perceptual implications of cochlear implant electrode-neuron interfacesR01DC012142 · NIDCD · UNIVERSITY OF WASHINGTON · PI JULIE G Arenberg · 2012 to 2026
$6.5M
Supplement for temporal bone histological tissue scanning equipmentR01DC012262 · NIDCD · UNIVERSITY OF MINNESOTA · PI OXENHAM, ANDREW J. · 2013 to 2023
$4.7M
NIDCD NIH HHS R01 DC012142NIDCD NIH HHS R01 DC012262
6 · The paper itself

Abstract

Cochlear implants (CIs) are considered effective at restoring some hearing abilities to individuals with severe hearing loss. However, there is considerable variability in performance outcomes among adults with CIs. One likely source of variability is the quality of the electrode-neuron interface (ENI), which describes how well implanted electrodes stimulate nearby spiral-ganglion neurons (SGNs) in the cochlea. Absolute thresholds, measured via focused electrical stimulation, have been proposed as a behavioral estimate of ENI. In this retrospective study, focused-stimulation threshold patterns were compared for 92 ears from 74 adult cochlear implant listeners with various etiologies, durations of deafness, and electrode array types. The results showed that CI listeners implanted with a pre-curved array tended to have lower overall focused thresholds than listeners with straight arrays, as well as a threshold profile with lower (better) thresholds at each end of the array and highest thresholds near the middle of the array. CI listeners with etiologies related to auto-immune dysfunction, such as Meniere's disease, tended to have the opposite profile, with lowest thresholds near the middle of the array. No significant effect of duration of deafness on focused thresholds was observed. Further investigation into which demographic and device factors affect focused thresholds, and therefore potentially ENI, could shed light on the variability of CI outcomes and guide development of individualized treatment strategies.

Indexed as

Auditory ThresholdCochlear ImplantationCochlear ImplantsDeafnessPersons with Hearing DisabilitiesAcoustic StimulationAdultAgedAged, 80 and overElectric StimulationFemaleHumansMaleMiddle AgedProsthesis DesignRetrospective Studiesarray typecochlear implantsetiologyfocused thresholds

Identifiers

PMID42711687
PMCPMC13554552

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.