Evidence map›Paper›PMID 42711670›Full record

ArticleJournal of biophotonics2026

Photoacoustic Imaging Reveals Early Hemodynamic Changes in Diabetic Nephropathy: Hemoglobin Rise Prior to Oxygen Saturation Drop.

Hong Wang, Jiazhi Cao, Jie Yang, Xijing Yang, Wenwu Ling

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of biophotonics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hong WangDepartment of Medical Ultrasound, West China Hospital, Sichuan University, Chengdu, China.
Jiazhi CaoDepartment of Medical Ultrasound, West China Hospital, Sichuan University, Chengdu, China.
Jie YangDepartment of Medical Ultrasound, West China Hospital, Sichuan University, Chengdu, China.
Xijing YangAnimal Experiment Centre of West China Hospital of Sichuan University, Chengdu, China.
Wenwu LingDepartment of Medical Ultrasound, West China Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0002-6449-3831

Funding

Sichuan Province Science and Technology Support Program 2024YFFK0228
6 · The paper itself

Abstract

objectiveThis study employed photoacoustic imaging (PAI) to dynamically monitor renal oxygen saturation (sO

methodsdb/db mice with fasting blood glucose (FBG) levels above 11.1 mmol/L (the model group) and C57BL/6 mice (the control group) were assessed at 8, 16, and 32 weeks of age. Evaluations included physiology, biochemistry, histology, and PAI.

resultsHistology confirmed progressive renal injury in db/db mice from 16 weeks. PAI quantification revealed a significant increase in HbT in db/db mice as early as 8 weeks, prior to a significant sO

conclusionThe rise in renal HbT precedes the fall in sO

Indexed as

Diabetic NephropathiesHemodynamicsHemoglobinsOxygenOxygen SaturationPhotoacoustic TechniquesAnimalsKidneyMaleMiceMice, Inbred C57BLHemoglobinsOxygendb/db micediabetic nephropathyhemoglobinoxygenationphotoacoustic imaging

Identifiers

PMID42711670
PMCPMC13553732

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.