Evidence map›Paper›PMID 42711637›Full record

ReviewObesity surgery2026

Tranexamic Acid Administration in Laparoscopic Sleeve Gastrectomy.

Magdy H Eldegwy, Hany O Ragab, Mohammed A Taha Alafifi, Ismail A Elzoughari, Hosni Ali Salem, Waleed Hamdy Shokr, Talal Saad Almukhlifi, Hatem Mahmoud Nasr Elkenany, Mohamed Hegab, Mohamed Ali Mahmoud and 4 more

Abstract readReview
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In one paragraph

Review in Obesity surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Magdy H EldegwyAl Azhar University, Cairo, Egypt. magdydegwy@gmail.com.
Hany O RagabAl Azhar University, Cairo, Egypt.
Mohammed A Taha AlafifiAl Azhar University, Cairo, Egypt.
Ismail A ElzoughariAl Azhar University, Cairo, Egypt.
Hosni Ali SalemAl Azhar University, Cairo, Egypt.
Waleed Hamdy ShokrCairo University, Giza, Egypt.
Talal Saad AlmukhlifiPrince Sattam Bin Abdulaziz University, Al Kharj, Saudi Arabia.ORCID http://orcid.org/0009-0005-1776-8977
Hatem Mahmoud Nasr ElkenanyAl Azhar University, Cairo, Egypt.
Mohamed HegabAl Azhar University, Cairo, Egypt.
Mohamed Ali MahmoudAl-Azhar University, Assiut, Egypt.ORCID http://orcid.org/0009-0009-1282-5628
Ayman Ahmed Abdeltawab EbrahimPrincess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Elsayed A AwadAl Azhar University, Cairo, Egypt.
Abdallah Elabd HassanAl Azhar University, Cairo, Egypt.ORCID http://orcid.org/0009-0005-4083-3407
Azza Mahrous ShaffikBenha University, Banhā, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimPerioperative bleeding remains one of the most frequent early complications of laparoscopic sleeve gastrectomy (LSG). The present work aimed to provide a thorough and updated systematic review and meta-analysis of the published studies on the use of tranexamic acid (TXA) in LSG.

methodsThe present study was conducted according to the Preferred Reporting Items for Systematic review and Meta-Analyses (PRISMA) guidelines. A systematic literature search was conducted in PubMed, Scopus, and Web of Science.

resultsThe present study analyzed 9 studies. They included 1665 patients. TXA was administered to 842 patients while 823 patients received no intervention or placebo. Pooled analysis revealed significantly shorter operative duration [mean difference (95% CI): -4.56 (-7.36, -1.76), p = 0.001], shorter length of hospital stay [mean difference (95% CI): -0.12 (-0.16, -0.08), p<0.00001] and lower reduction of preoperative hemoglobin levels in the TXA arm [mean difference (95% CI): -0.2 (-0.38, -0.02), p = 0.03]. No significant differences were found between the interventional arms regarding number of used intraoperative hemostatic clips [mean difference (95% CI): -0.2 (-0.93, 0.53), p = 0.59], number of patients requiring blood transfusion [RD (95% CI): -0.01 (-0.02, 0.0), p = 0.08] or number of patients requiring reoperation for bleeding [RD (95% CI): -0.01 (-0.03, 0.0), p = 0.12]. No thromboembolic events were reported.

conclusionsThe present study suggests that, based on the currently available evidence, intraoperative administration of TXA is associated with lower reduction of preoperative hemoglobin levels in patients undergoing LSG, which may contribute to shorter operative duration and reduced length of hospital stay.

Indexed as

Bariatric surgeryLaparoscopic sleeve gastrectomyStable line bleedingTranexamic acid

Identifiers

PMID42711637

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.